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ID 16279
Eprint ID
16279
FullText URL
Thumnail 98_465.pdf 418 KB
Title Alternative
Helix pomatia A hemagglutinin binding activity to peripheral T-lymphocytes in malignant digestive tract diseases Part 2: Clinical studies
Author
Yasuhara, Takashi
Abstract
Helix pomatia A hemagglutinin (HP) binding activity, a surface marker of peripheral T cells, to neuraminidase-treated peripheral T cells was studied in patients with digestive tract cancer or benign liver disease and in normal subjects. The HP binding activity (ng/10(6) T cells) to T cell subpopulations in peripheral lymphocytes was calculated as: (Amount of bound HP to total peripheral lymphocytes (ng/10(6) cells)) / (Ratio of T cells to total peripheral lymphocytes (%)) × 100. The calculated HP binding activity to T cells was significantly higher in digestive tract cancer patients than in benign liver disease patients (p<0.05) and normal subjects (p<0.01). These results suggest that either the subsets of peripheral T cells with high HP binding activity may be significantly increased or HP receptors of all peripheral T cells may be increased to the same degree in digestive tract cancer patients. This activity may be a useful index of cellular immunity in digestive tract cancer patients, although it seems to have no relevance to the progression of cancer.
Keywords
Helix pomatia A hemagglutinin
結合活性
消化器癌
末梢血T cell
neuraminidase
Published Date
1986-06-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume98
Issue
issue5-6
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
465
End Page
473
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/98/5-6/98_5-6_465/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma