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ID 16302
Eprint ID
16302
FullText URL
Thumnail 98_587.pdf 351 KB
Title Alternative
The effect of chlorinated monoaromatic hydrocarbons on biological membranes(Comparison of the effect of chlorobenzenes and chlorophenols on biomembranes)
Author
Mori, Takaaki
Abstract
A comparative study on the effect of chlorobenzenes and chlorophenols on mitochondrial membranes was conducted. An increase in chlorine residue from both chlorobenzenes and chlorophenols caused a decrease in respiratory control index (RCI). Chlorophenols acted on biomembranes at a lower concentration than chlorobenzenes. The compounds decreased RCI by increasing state 4 respiration and decreasing state 3 respiration. As the number of chlorine atoms on chlorobenzenes increased, state 3 respiration decreased, causing a decrease in RCI. As the number of chlorine atoms on chlorophenols increased, state 4 respiration increased, causing a decreased in RCI. The amount of potassium released from mitochondrial membranes increased with time after addition of dichlorobenzene and dichlorophenol. A logarithmic increase in potassium release vs. time was observed with dichlorobenzene, and a liner increase in potassium release was observed with dichlorophenol.
Keywords
ミトコンドリア
酸化的リン酸化反応
塩化ベンゼン類
塩化フェノール類
K(+)遊出作用
Published Date
1986-08-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume98
Issue
issue7-8
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
587
End Page
597
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/98/7-8/98_7-8_587/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma