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ID 16350
Eprint ID
16350
FullText URL
Thumnail 95_721.pdf 2.89 MB
Title Alternative
Studies on cell-mediated immunity in patients with malignant tumor. Part II. Leukocyte migration inhibition test in patients with malignant lymphoma.
Author
Terao, Seiya
Abstract
Three different procedures of the leukocyte migration inhibition test(LMIT) were performed in order to study cell-mediated immunity in patients with malignant lymphoma. Using sonicated antigens from normal lymphocytes and lymphoma cells obtained by lymphnode biopsy, leukocytes from patients with malignant lymphoma showed a positive reaction exclusively against antigens obtained from malignant lymphoma cells. It was suggested that patients with malignant lymphoma had a cell-mediated immunity against the tumor-associated antigens. The migration index of LMIT using autochthonous antigen was significantly lower than that using allogeneic antigen. In LMITs using 3M KCI extracts of established lymphoid cell lines, it was suggested that there were both tumor-associated antigens and leukemia-lymphoma associated antigens in the extracts. The serum immuno-suppressive factor was positive in 40 of 50 patients' sera(80%) in LMITs. The suppressive ratio and immune complex levels of the sera from patients with extensive disease was significantly higher than that of patients with localized disease. Studies on cell-mediated immunity in patients with malignant tumor.
Keywords
leukocyte migration inhibition test
malignant lymphoma
Published Date
1983-08-31
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume95
Issue
issue7-8
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
721
End Page
729
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/95/7-8/95_7-8_721/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma