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ID 16443
Eprint ID
16443
FullText URL
Thumnail 96_585.pdf 4.71 MB
Title Alternative
Pathomorphological study of malformed ossicles in the mousefetus caused by maternal hypervitaminosis A
Author
Kajihara, Masayuki
Abstract
Pregnant ddN mice were injected with 15,000 I.U. of water miscible vitamin A intraperitoneally on day 8 of pregnancy. Fetuses were removed surgically on day 18. Twenty of them were selected randomly to be sectioned horizontally and stained with hematoxylin and eosin solution for histological observation of the malformed ossicles. The malleus, incus and stapes were suggested by the observations to have developed directly from branchial arch cartilage: the former two from Meckel's cartilage and the latter from Reichert's cartilage. That the stapes was isolated might lend support to the theory of dual origin of the footplate. The above results were discussed with embryological and bibliographical considerations.
Keywords
hypervitaminosis A (ビタミンA過剰投与)
mouse fetus (マウス胎仔)
malformed ossicles (耳小骨奇形)
Published Date
1984-04-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume96
Issue
issue5-6
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
585
End Page
599
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/96/5-6/96_5-6_585/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma