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ID 19537
Eprint ID
19537
FullText URL
Thumnail 68_769.pdf 2.6 MB
Title Alternative
Studies on the Effect of Adrenalin, Cortisone and ACTH on the White Blood Cell especially on the Eosinophilic Leukocyte by the Tissue Culture of the Bone Marrow - mainly on the mechanism of eosinopenia - Part (Ⅱ) Influences on the same drugs (adrenalin, cortisone and ACTH) on the peripheral and bone marrow eosinophilic leucocyte of hypophysectomized dogs (mainly by bone marrow culture)
Author
Yamamoto, Shinro
Abstract
I have studied adrenalin, cortisone and ACTH eosinopenia in hypophysectomized dogs by means of chamber counting. In addition, the bone marrow of hypophysectomized dogs was cultivated in using the plasma of normal and hypophysectomized dogs separately, cortisone was added to each preparate. The results obtained are as follows: (1) Adrenalin eosinopeia is due to its direct influence upon the eosinophil partly through the pituitary body. (2) ACTH acts as glucocorticoid in ACTH cosinopenia. This brings about the similar result to cortisone eosinopenia. But ACTH eosinopenia has no correlation with the function of the pituitary anterior lobe, while cortisone eosinopenia requires the normal function of the anterior lobe. (3) Cortisone (compound E) alone can not cause cortisone eosinopenia but it gives hypofunctional influence and developmental disturbance upon the eosinophil in synergism of other compounds. (4) The normal functions of both the adrenal cortex and pituitary anterior lobe is necessary for eosinopenia by cortisone administration. (5) Cortisone test can be used as a test of pituitary anterior lobe function only in the case with normal adrenocortical function.
Published Date
1956-07-31
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume68
Issue
issue7
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
769
End Page
781
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/68/7/68_7_769/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
OAI-PMH Set
岡山大学
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma