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ID 21147
Eprint ID
21147
Title Alternative
Ketamine-amitriptyline therapy for the intractable cancer pain with restlessness
Author
Noishiki, Yasuharu
Abstract
A combination therapy of ketamine-amtriptyline for the intractable pain with restlessness of cancer patients in the end stage was presented. Seven patients with peritonitis carcinomatosis due to recurrence of stomach cancer were administrated the therapy. They ranged in age from 29 to 79 years. The results were eminently desirable. Intractable pain with restlessness were diminished by the therapy though languid feeling was yet remained. Anodyne (pentazocine), which was nessesary many times in one day before the therapy, was not used in the duration of the therapy. The experimental and clinical studies of analgesic property of ketamine by HATANO revealed that it is more twice as potent an analgesic in low dosage compared with pethidine, despite its rather short duration of action. There was no respiratory depression. No hypotension nor bradycardia were observed during the therapy. The only use of ketamine however, could not release the pain and anguish of cancer patients. The author applied amitriptyline to these cases. The combination use of ketamine and amitriptyline could release them. These drugs demonstrated their full effect by the combination use.
Note
原著論文 (Original Papers)
Published Date
1981-03-25
Publication Title
岡山大学温泉研究所報告
Publication Title Alternative
Papers of the Institute for Thermal Spring Research, Okayama University
Volume
volume51
Publisher
岡山大学温泉研究所
Publisher Alternative
Institute for Thermal Spring Research, Okayama University
Start Page
21
End Page
23
ISSN
0369-7142
NCID
AN00032853
Content Type
Departmental Bulletin Paper
language
日本語
File Version
publisher
Refereed
False
Eprints Journal Name
mmc