ID 40135
JaLCDOI
FullText URL
Author
Pavelić, Jasminka
Čulić, Srdjana
Čulić, Vida
Abstract
The occurrence of Langerhans cell histiocytosis (LCH) and another malignancy in the same patient is infrequent but has been recognized. The genetic changes that could be responsible for LCH and/or concomitant leukemia development are obscure. To the best of our knowledge, this is the first description of constitutional maternally derived inv (9) (p12;q13) in an LCH patient, and also of the development of common ALL Ph after LCH diagnosis and therapy. The potential significance of these findings [inv (9)LCHALL Ph] and their mutual relationship are unknown. Therefore, cooperative studies of large numbers of patients are needed to identify the common risk factors, if any.
Keywords
acute lymphoblastic leukemia
genetic changes
langerhans cell histiocytosis
Amo Type
Case Report
Published Date
2010-08
Publication Title
Acta Medica Okayama
Volume
volume64
Issue
issue4
Publisher
Okayama University Medical School
Start Page
263
End Page
265
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
英語
Copyright Holders
Okayama University Medical School
File Version
publisher
Refereed
True
PubMed ID
Web of Sience KeyUT