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Title Alternative
Pathophysiological studies of bronchial asthma Part 1. Measurement and evaluation of Candida-specific IgG antibodies using an enzyme-linked immunosorbent assay
Author
Kitani, Hikaru
Abstract
To evaluate IgG-related mechanisms in bronchial asthma, Candida-specific IgG antibodies were estimated in 130 patients with bronchial asthma, using an enzyme-linked immunosorbent assay. In 41 healthy subjects, the levels of Candida-specific IgG antibodies were 0.595±0.465. In 130 asthmatics, the levels of Candida-specific IgG antibodies were 0.792±0.524. The difference in the levels of Candida-specific IgG antibodies between healthy subjects and asthmatics was more remarkable in cases from 0-20 years and 41-50 years of age. In cases with a negative delayed skin reaction to Candida, the levels of Candida-specific IgG antibodies were higher than in cases with a positive delayed skin reaction. There was a slight, but not significant correlation between the levels of Candida-specific IgG antibodies and disease severity. There was a significant correlation between the levels of Candida-specific IgG antibodies and precipitating antibodies to Candida. In conclusion, the analysis of Candida-specific IgG antibodies is useful in the evaluation of the pathophysiological mechanisms of bronchial asthma.
Keywords
酵素免疫抗体法
気管支喘息
カンジダ
特異的IgG抗体
Published Date
1990-06
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume102
Issue
issue5-6
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
559
End Page
569
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/102/5-6/102_5-6_559/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma