岡山大学環境理工学部研究報告 ISSN 2187-6940
Published by Faculty of Environmental Science and Technology, Okayama University

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The prevalence of Plasmodium vivax in Vanuatu Islands: Computer simulation of malaria control trails

Ishii, Akira
Kaneko, Akira
Abstract
We have estimated the degree of transmission of Plasmodium vivax malaria in Vanuatu Islands, eastern Melanesia with the aid of the computer simulations, which has been carried out on the platform of a mathematical transmission model. The malaria caused by Plasmodium vivax has a relapse character, which arises from hypnozoites in the liver. This phenomen makes a malaria control strategy difficult. When the mass drug administration is executed, the prevalence of Plasmodium vivax decreases moderately as compared with that of Plasmodium falciparum, and it recovers before long being affected by the relapses. The simulations suggest that one cannot attain the eradication of Plasmodium vivax malaria without the concentrated execution of the mass drug administration and the vector control that fairly reduces the vactorial capacity.
Keywords
Plasmodium vivax
computer simulation
hypnozoite
mass drug administration
relapse
ISSN
1341-9099
NCID
AN10529213