Journal of Okayama Medical Association
Published by Okayama Medical Association

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ユスリカ喘息における交差反応性の検討―オオユスリカ,アカムシユスリカ,セスジユスリカの比較検討―

Kitani, Hikaru
Mifune, Takashi
Kawauchi, Kazuhisa
Okazaki, Morihiro
Tanizaki, Yoshiro
Takahashi, Hisaho
Tada, Sinya
Takahashi, Kiyoshi
Kimura, Ikuro
Ishii, Akira
Abstract
In order to better understand the characteristics of bronchial asthma caused by chironomid midges, cross-reactivity of midges was examined in 163 asthmatics through observation of skin reactions and specific IgE and histamine release. Positive skin reactions were observed in 17 of 73 asthmatics (23.3%) for Chironomus plumosus, 89 of 276 (32.2%) of those for Tokunagayusurika akamusi, and 33 of 128 (25.8%) of those for Chironomus yoshimatsui. Two cases of 32 (6.3%) asthmatics for Chironomus plumosus, 16 of 144 (11.1%) of those for Tokunagayusurika akamusi, and 7 of 77 (9.1%) of those for Chironomus yoshimatsui showed a significant amount of histamine release (more than 15%). Cross-reactivity was present for Chironomus plumosus, Tokunagayusurika akamusi, Chironomus yoshimatsui, by both skin tests and basophil histamine release. It is suggested that both the male and female of Chironomus plumosus have common antigenecity, and cross-reactivity was observed between them.
Keywords
気管支喘息
ユスリカ
昆虫アレルギー
交差反応性
ISSN
0030-1558
NCID
AN00032489