Journal of Okayama Medical Association
Published by Okayama Medical Association

<Availability>
Full-text articles are available 3 years after publication.

Rituximab併用CHOP療法が奏効した肝原発びまん性大細胞型B細胞リンパ腫の1例

Okada, Hiroshi
Fujii, Soichiro
Watanabe, Kentaro
Shigematu, Terunobu
Miyashita, Katsuhiro
Okazaki, Morihiro
Kobashi, Haruhiko
Yokoyama, Motohiro
Thumnail 127_209.pdf 10.4 MB
Abstract
 A 78-year-old Japanese man was referred to our hospital after experiencing black feces. No abnormal finding was detected in the endoscopic examination of his stomach and large intestines. Computed tomography (CT) of the abdomen revealed a tumor lesion in the right lobe of the liver. A needle biopsy of the tumor under ultrasound guidance was performed. A pathological examination of the biopsy specimen showed a diffuse proliferation of lymphoma cells, which was compatible with diffuse large B-cell lymphoma (DLBCL). F-fluorodeoxyglucose (FDG)-positron emission tomography (PET)-CT demonstrated increased FDG uptake only in the liver tumor. We made the diagnosis of primary DLBCL of the liver. After six cycles of rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisolone (R-CHOP), the patient achieved complete remission and has maintained remission for 2 years since the diagnosis. The R-CHOP regimen might be effective therapy for primary DLBCL of the liver.
Keywords
びまん性大細胞型B細胞リンパ腫(diffuse large B-cell lymphoma)
肝臓(liver)
R-CHOP療法(R-CHOP regimen)
Note
症例報告(Case Reports)
ISSN
0030-1558
NCID
AN00032489
DOI
NAID