Journal of Okayama Medical Association
Published by Okayama Medical Association

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Full-text articles are available 3 years after publication.

ラット肝上清中に存在する細胞増殖抑制因子について

Kuramitsu, Makoto
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Abstract
The activities and properties of two inhibitors of cell proliferation, which are present in the supernatant of rat liver, have been studied in L(929) fibloblast systems. 1) One factor, which had arginase activity, completely inhibited cell proliferation by depletion of arginine in the culture medium. 2) The other factor was stable to Trypsin-, RNase and Heat-treatment, and primarily inhibited protein synthesis. Inhibition of DNA synthesis was thought to be a secondary effect. 3) Whether the second factor changes the biological activity in regenerating liver is now under investigation.
Keywords
細胞増殖抑制因子
ラット肝上清
L細胞
ISSN
0030-1558
NCID
AN00032489