Published by Misasa Medical Center, Okayama University Medical School
Published by Misasa Medical Center, Okayama University Medical School

<Formerly known as>
岡大三朝分院研究報告 (63号-72号) 環境病態研報告 (57号-62号)
岡山大学温泉研究所報告 (5号-56号) 放射能泉研究所報告 (1号-4号)

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Studies on the release of histamine from basophils 1. Determination of histamine from whole blood by an automated fluorometric histamine analysis system

Tanizaki, Yoshiro
Komagoe, Haruki
Sudo, Michiyasu
Mifune, Masaaki
Morinaga, Hiroshi
Ohtani, Jun
Kitani, Hikaru
Goda, Yoshinori
Tada, Shinya
Kimura, Ikuro
Abstract
Histamine released from whole blood was determined by an automated fiuorometric histamine analysis system. The increased release of histamine from basophils by anti-IgE was observed in ten healthy subjects and 12 extrinsic asthma patients, while the release in 11 intrinsic asthma patients was significantly less as compared to that in healthy and extrinsic asthma subjects. House dust extract caused a significant increase in the histamine release from basophils of the extrinsic asthma patients who are sensitive to house dust. It was concluded from this study that histamine released from basophils could be easily determined by an automated analysis system and that the method is useful for the diagnosis and study of allergy.
Note
原著論文 (Original Papers)
ISSN
0369-7142
NCID
AN00032853