Author 光延 文裕|
Published Date 2005-01-31
Publication Title 岡山医学会雑誌
Volume volume116
Issue issue3
Content Type Journal Article
JaLCDOI 10.18926/14921
Title Alternative Spa therapy for patients with asthma. A study on 437 patients with asthma admitted for last 5 years.
FullText URL 070_001_008.pdf
Author Tanizaki, Yoshiro| Mitsunobu, Fumihiro| Mifune, Takashi| Hosaki, Yasuhiro| Ashida, Kozo| Tsugeno, Hirofumi| Okamoto, Makoto| Harada, Seishi| Takata, Shingo| Ochi, Koji|
Abstract 1994年1月より1998年12月までの5年間に当院へ入院した呼吸器疾患のなかで気管支喘息を対象に,年齢,地域分布などの経年変化について検討を加えた。1.最近5年間に当院へ入院した呼吸器疾患患者は664例で,このうち,気管支喘息は437例(65.8% )であった。呼吸器疾患のなかで気管支喘息に占める割合の経年変化では,1995年度が最も高く(74.4% ),1997,1998年度にはやや低下(ともに60.7% )の傾向が見られた。2.入院患者の地域分布では,鳥取県内からの入院患者に比べ,遠隔地(鳥取県外)からの入院患者が比較的多く,いずれの年度においても50% 以上(平均57.3% )であった。また,岡山,大阪,兵庫,広島,山口,愛媛県などからの入院症例が多い傾向か見られた。3.年齢別検討では,いずれの地域においても,高齢者の入院症例か多く,鳥取県内では70才以上の症例の頻度(平均35.1% )が,また遠隔地(鳥取県外)では60-69才の症例の頻度(平均37.7% )が高い傾向か見られた。
Abstract Alternative The parients with asthma who were admitted at our hospital for last 5 years (1994-1998) were examined in relation to age and areas where patients came. 1. Of 664 patients with respiratory disease admitted for last 5 years, 437 patients (65.8% ) had asthma. The frequency of asthma in all patients with respiratory disease was the highest (74.4% ) in 1995, and decreased in 1997 and 1998 (60.7% ). 2. The number of patients with asthma from distant areas (outside Tottori prefecture) was constantly larger than the number of those inside Tottori prefecture in each year. The number of patients from Okayama, Osaka, Hyogo, Hiroshima, Yamaguchi, and Ehime was larger than the number from other distant areas. 3. Regarding the distribution of age of these patients, the number of patients over the age of 60 was more frequently observed, regardless of the area where patients came. Larger number of patients over the age of 70 (35.1% ) was found in those inside Tottori prefecture, while the number of patients between the ages of 60 and 69 (37.7% ) was larger in those from distant areas.
Keywords 気管支喘息 (asthma) 温泉療法 (spa therapy) 高齢患者 (aged patients) 遠隔地 (distant area)
Publication Title 岡大三朝分院研究報告
Published Date 1999-12
Volume volume70
Start Page 1
End Page 8
ISSN 0918-7839
language 日本語
File Version publisher
NAID 120002308420
Author Tanizaki, Yoshiro| Kitani, Hikaru| Okazaki, Morihiro| Mifune, Takashi| Mitsunobu, Fumihiro| Sugimoto, Keisuke|
Published Date 1993
Publication Title 岡山医学会雑誌
Volume volume105
Issue issue3-4
Content Type Journal Article
JaLCDOI 10.18926/14985
Title Alternative Dietary supplementation in bronchial asthma. Suppression of the generation of leukotrienes by N-3 fatty acids.
FullText URL 068_041_044.pdf
Author Ashida, Kozo| Mitsunobu, Fumihiro| Mifune, Takashi| Hosaki, Yasuhiro| Tsugeno, Hirofumi| Okamoto, Makoto| Iwagaki, Naofumi| Tanizaki, Yoshiro| Tsuji, Takao| Yamamoto, Junko| Okita, Misako|
Abstract N-3系脂肪酸の気管支喘息に対する有用性が示唆されているが,その評価は定まっていない。今回,5人の気管支喘息患者に対しN-3系脂肪酸であるαリノレン酸を豊富に含有するエゴマ油を用いた食事療法を行い,臨床症状,ピークフロー値,末梢白血球からのロイコトリエン産生能,血漿リン脂質中の脂肪酸組成につき検討を行った。2週間の食事療法の前後でピークフロー値は有意な改善を示し(p<0.05),カルシウムイオノファー刺激によるロイコトリエン(LT)産生能は治療前後でLTB4が77.6ng/5×106cellsから41.6ng/5×10(6)cells(p<0.05)に,LTC4は64.0ng/5×10(6)cellsから38・8ng/5×10(6)cells(p<0.05)とともに有意な改善を認めた。また血漿リン脂質中のN-3系脂肪酸(αリノレン酸,エイコサペンタエン酸,ドコサヘキサエン酸)も有意な上昇を認めた。以上よりN-3系脂肪酸(エゴマ油)を用いた食事療法の有用性が示唆された。
Abstract Alternative The therapeutic trials using N-3 fatty acids such as fish oil have been reported in patients with bronchial asthma, while its effect is still controversial. The effects of dietary supplementation with perilla seed oil rich in alpha-linolenic acid (α-LNA), parent n-3 fatty acid, were studied in five patients with asthma. The symptoms of asthma and mean peak flow rates (PFR) both early in the morning and in the evening were improved 2 weeks after the dietary supplementation and the increases of peak flow rates were significant (p<0.05). The generation of leukotriene B4 (LB4) by peripheral leukocytes stimulated with Ca ionophore A23187 was significantly suppressed from 77.6 ng/5×10(6) cells to 41.6ng/5×10(6) cells by the supplementation (P<0.05). The generation of leukotriene C4 (LTC4) by leukocytes was also significantly suppressed from 64.0 ng/5×10(6) cells to 38.8ng/5×10(6) cells after the manipulation with perilla seed oil (P<0.05). The concentration of N-3 fatty acids (such as α-LNA, eicosapentaenoic, and docosahekisaenoic acids) in plasma phospholipid increased significantly after the dietary supplementation (P<0.05). These results suggest that dietary supplementation with perilla seed oil is beneficial for the treatment of asthma.
Keywords シソ油 (perilla seed oil) 気管支喘息 (bronchial asthma) ロイコトリエンB4 (LTB4) ロイコトリエンC4 (LTC4) 脂肪酸 (fatty acids)
Publication Title 岡大三朝分院研究報告
Published Date 1997-12
Volume volume68
Start Page 41
End Page 44
ISSN 0918-7839
language 日本語
File Version publisher
NAID 120002308166
Author 北村 佳久| 三宅 悟| 横山 紀子| 川上 英治| 荒木 博陽| 柴田 和彦| 五味田 裕| Mitsunobu, Fumihiro| Tanizaki, Yoshiro|
Published Date 2004-02-01
Publication Title 岡大三朝医療センター研究報告
Volume volume74
Content Type Departmental Bulletin Paper
Author Mifune, Takashi| Kawaraya, Masashi| Hiramatsu, Junichi| Yokota, Satoshi| Sugimoto, Keisuke| Kajimoto, Kazuhiro| Mitsunobu, Fumihiro| Kitani, Hikaru| Tanizaki, Yoshiro|
Published Date 1993
Publication Title 岡山医学会雑誌
Volume volume105
Issue issue5-6
Content Type Journal Article
Author Mitsunobu, Fumihiro| Mifune, Takashi| Kitani, Hikaru| Okazaki, Morihiro| Tanizaki, Yoshiro|
Published Date 1993
Publication Title 岡山医学会雑誌
Volume volume105
Issue issue3-4
Content Type Journal Article
JaLCDOI 10.18926/15123
Title Alternative T cell subpopulation and asthma classification
FullText URL 066_044_048.pdf
Author Mifune, Takashi| Yokota, Satoshi| Hosaki, Yasuhiro| Kajimoto, Kazuhiro| Mitsunobu, Fumihiro| Tanizaki, Yoshiro|
Abstract 気管支喘息症例の臨床病型に対するTリンパ球の役割を明らかにするために,気管支肺胞洗浄液中のCD3,CD4,CD8陽性細胞の比率を検討した。1.Ia気管支攣縮型におけるCD3陽性細胞は75.6±6.52%,Ib:過分泌型では75.4±16.5%,Ⅱ:細気管支閉塞型では61.0±12.5%であり,いずれの病型においても有意な差は認められなかった。2.CD4陽性細胞についてはIa型47.4±6.11%,Ib型39.5±8.70%,Ⅱ型46.3±6.91%,CD8陽性細胞についてはIa型28.3±8.77%,Ib型35.5±12.3%,Ⅱ型29.4±11.5%と過分泌型 で他の2病型とは違う傾向を示したが,有意ではなかった。3.活性化を示すHLA-DR陽性細胞はCD4,CD8陽性細胞とも気管支攣縮型で高い傾向が認 められたが有意ではなかった。以上,今回の検討では各臨床病型間でTリンパ球の関与に明らかな差は見られなかったが,気管支攣縮型に対する活性型Tリンパ球より強い関与の可能性が示唆された。
Abstract Alternative To clarify the role of T lymphocyte to patho physio logical changls in He aiways, the relationship between T cell subpopulation in BALF and each clinical asthma type were investigated. The proportion of BALF CD3 +T cells in patients with Ia : simple bronchoconstriction type was 75.6±6.52%, 75.4±16.5% in those with Ib : hypersecretion type and 61.0±12.5% in those with Ⅱ : bronchiolar obstruction type. No siginificant differences were observed between 3 asthma types. The proportion of BALF CD4 +T cells and CD8 +T cells revealed different tendency in patients with type Ib, compaired to patients with type Ia or type Ⅱ, but this was not significant. A higher proportion of CD4 + and CD8 +T cells in BALF expressing the T cell activation marker HLA-DR was observed in patients with type Ia. compared to those with other clinial asthma types. However, these were not significant.
Keywords 気管支喘息臨床病型 (clinical type of beonchial asthma) Tリンパ球 (T-lymphocyte) CD4陽性リンパ球 (CD4+lymphocyte) CD8陽性リンパ球 (CD8+lymphocyte) 活性化リンパ球 (activated lymphocyte)
Publication Title 岡大三朝分院研究報告
Published Date 1995-09
Volume volume66
Start Page 44
End Page 48
ISSN 0918-7839
language 日本語
File Version publisher
NAID 120002307211
JaLCDOI 10.18926/15160
Title Alternative A case report of mixed connective tissue disease.
FullText URL 065_096_100.pdf
Author Takata, Ichiro| Kitani, Hikaru| Mifune, Takashi| Mitsunobu, Fumihiro| Kajimoto, Kazuhiro| Matsumura, Tadashi| Yokota, Satoshi| Tanizaki, Yoshiro|
Abstract 症例は50歳女性で,1991年頃より両肘関節の疼痛とレイノー現象を自覚するようになり前医にて慢性関節リウマチ(Rheumatoid arthritis, 以下RAと略)との診断を受け加療受けるも症状の改善なく,当科を受診した。典型的な慢性関節リウマチの症状に乏しく,他の膠原病の存在を疑って検索したところ,抗RNP抗体陽性等の所見から,混合性結合組織病(mixed connective tissue disease, 以下MCTDと略)と診断した。MCTDは初診時に慢性関節リウマチと誤診される例が多く,慢性関節リウマチに非典型的な症状を伴う場合は,MCTDが鑑別診断として重要と考えられた。
Abstract Alternative A 50-year-old woman, diagnosed as rheumatoid arthritis (RA) in 1991, had been treated with Lobenzarit disodium and non steroidal anti-inflammatory drugs (NSAIDs) before administration at our hospital. Despite the treatment with these drugs, her symptoms did not improve. She was admitted to our hospital for her progressive bilateral elbow joint pain and Raynaud's phenomenon. Although abnormal values of laboratory examinations such as an increased ESR (64mm/1hr), increased level of serum IgG (2854mg/㎗) and a positive RA test were shown, the clinical features of classical RA were not clear. There, she was diagnosed as mixed connective tissue disease (MCTD), because of high level of anti-RNP antibody in serum, Raynaud's phenomenom, multiple arthritis and constrictive ventilatory disturbance. Her symptoms and the results of labolatory examinations were clearly improved by glucocorticoid therapy.
Keywords 混合性結合組織病 (MCTD) 慢性関節リウマチ (Rheumatoid arthritis) 抗RNP抗体 (Anti-RNP antibody)
Publication Title 岡大三朝分院研究報告
Published Date 1994-09
Volume volume65
Start Page 96
End Page 100
ISSN 0918-7839
language 日本語
File Version publisher
NAID 120002307772
Author Yokoi, Tadashi| Senda, Masuo| Hamada, Masanori| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Ashida, Kozo| Iwagaki, Naofumi| Nagata, Takuya| Fujii, Makoto| Takata, Shingo| Tanizaki, Yoshiro| Inoue, Hajime|
Published Date 2004-02-01
Publication Title 岡大三朝医療センター研究報告
Volume volume74
Content Type Departmental Bulletin Paper
Author Yokoi, Tadashi| Senda, Masuo| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Ashida, Kozo| Nishida, Norikazu| Tsugeno, Hirofumi| Okamoto, Makoto| Nagata, Takuya| Takata, Shingo| Tanizaki, Yoshiro| Inoue, Hajime|
Published Date 2003-02-01
Publication Title 岡大三朝医療センター研究報告
Volume volume73
Content Type Departmental Bulletin Paper
JaLCDOI 10.18926/15127
Title Alternative Spa therapy and quality of life in patients with bronchial asthma
FullText URL 066_072_077.pdf
Author Tanizaki, Yoshiro| Mifune, Takashi| Mitsunobu, Fumihiro| Kajimoto, Kazuhiro| Hosaki, Yasuhiro| Yokota, Satoshi| Ochi, Koji| Harada, Hideo| Ikeda, Satoru| Taketa, Kazuhisa|
Abstract 気管支喘息のなかでも,ステロイド依存性重症難治性喘息では,気管支拡張薬その他の抗喘息薬のみでは発作のコントロ-ルが極めて困難であり,したがって副腎皮質ホルモンの長期投与を余儀なくされる。そして,投与薬剤,特に気管支拡張薬の心臓刺激作用や副腎皮質ホルモンの副作用,さらには運動誘発喘息がひき起こされやすいなどの理由により,体動制限が加えられることが多い。このことが,また精神活動の低下へとつながる。したがって,重症難治性喘息患者のQuality of life (QOL)を高めるためには,薬剤の副作用をできるだけ低くするための投与薬剤の減量をはかるとともに,十分な運動のもとに治療を行い全身状態の改善,それにともなう精神活動の活性化をはかる必要がある。かかる観点からすれば,温泉療法は最も理想的な治療法であり,その直接作用(気道への作用:気道浄化作用,気道粘膜正常化作用)により,白,他覚症状の改善,換気機能の改善,気道過敏性の低下などが観察される。また,間接作用(気道以外への作用)により,全身状態の改善,自律神経系の安定化作用,副腎皮質機能の改善作用などが見られる。すなわち,重症難治性喘息に対する温泉療法では,十分な運動のもとに,精神活動の活性化をともなった喘息症状の改善がはかられるため,患者のQOLをより一層高めることができると判断される。
Abstract Alternative Bronchial asthma is in qeneral a disease with good prognosis and can be controlled with usual antiasthmatic drugs. However, there are some patients whose asthma attacks can be controlled only with use of qlucocorticoids. In these patients, adverse side effects of many kinds of drugs containing bronchodilators and qlucocorticoids, and exercise-induced asthma attacks are often observed. Thus, the patients have to keep limitation of exercise during treatment of their asthma attacks, leading to decrease psychical activity. Complex spa therapy for bronchial asthma consists of swimming training in a hot spring pool (exercise), inhalation of iodine salt solution and fango therapy. Spa therapy has two kinds of actions : direct action to airways and indirect action to other organs except airways. The direct action of spa therapy improves subjective and objective symptoms, and ventilatory function, and suppress bronchial hyperresponsiveness. In contrast, improvemment of suppressed function of adrenocortical glands, of mental activity, and of autonomic nerve system is observed as indirect action of spa therapy. These actions play an important role for improvement of QOL of patients with bronchial asthma.
Keywords 温泉療法 (spa therapy) 重症難治性喘息 (lntractable asthma) 運動 (exercise) 精神活動 (phychical activity) QOL
Publication Title 岡大三朝分院研究報告
Published Date 1995-09
Volume volume66
Start Page 72
End Page 77
ISSN 0918-7839
language 日本語
File Version publisher
NAID 120002307919
JaLCDOI 10.18926/14841
Title Alternative Two male steroid-dependent asthmatics treated with etidronate
FullText URL 72_062_065.pdf
Author Tsugeno, Hirofumi| Okamoto, Makoto| Takata, Singo| Yokoi, Tadashi| Nishida, Kazunori| Ashida, Kozo| Hosaki, Yasuhiro| Mitsunobu, Fumihiro| Tanizaki, Yoshiro| Nakai, Mutsuo| Akiyama, Tsuneo| Hasegawa, Hisakazu| Tsuji, Takao|
Abstract 男性のステロイド依存性気管支喘息患者にエチドロネートを4年間の長期間にわたり投与した経験を得たので報告する。症例は,男性のステロイド依存性気管支喘息で,エチドロネート200mg/日・14日間投与を4ケ月おきに4年間にわたり反復投与し,活性型ビタミンD製剤 (VD)投与と併用した2例と,活性型VD製剤を単独授与した2例。椎体圧迫骨折数,境骨耗骨密度,海綿骨骨密度,皮質骨骨密度について,椎体X線像,PQCT(Stratec XCT960)を用いて4ケ月毎に測定し,48ケ月後の効果を検討した。エチドロネートを投与した症例1では,総骨密度と海綿骨はやや増加を認め皮質骨密度は減少していた。エチドロネートを授与した症例2では,総骨密度,海綿骨,皮質骨密度はいずれも減少を認めたが,VD単独投与した2例よりもやや減少が抑制されていたようであった。VD単独投与した2例ではいずれの項目も減少を認めた。これらの症例からは,エチドロネートは男性のステロイドによる骨傷害にも有効と考えられたが,現在投与継続途中であり,今後さらに検討を続ける必要がある。
Abstract Alternative We report an experience about administration of etidronate to male steroid-dependent asthmatics for a long time. For 4 years, two men with steroid-dependent asthma were treated with etidronate (200 mg / day, for 14 days) every 4 months and 25-hydroxyvitamin D3 (VD) together, and two patients were treated with VD alone. Vertebral fractures were evaluated by the lateral spinal X-ray films, and radial total bone mineral density (BMD) , trabecular BMD and the cortical BMD were measured by pQCT (Stratec XCT960) every four months. Trabecular and total BMD increased but cortical BMD decreased in the case 1 who was treated with both etidronate and VD. In the case 2 with etidronate and VD treatments, total and trabecular BMD decreased, but reduction of these indices seemed to be more suppressed than that in two patients with VD alone. According to these experiences, etidronate may be effective against the steroid-induced bone injury in men. Since periods treatment are not en-ough long to evaluate therapeutic effect of etid-ronate, we will have to continue the examination of these cases further more from now on.
Keywords エチドロネート 男性 ステロイド 気管支喘息
Publication Title 岡大三朝分院研究報告
Published Date 2002-02-01
Volume volume72
Start Page 62
End Page 65
ISSN 0918-7839
language 日本語
File Version publisher
NAID 120002308188
Title Alternative The 84th Annual Meeting of the Japanese Society of Balneology, Climatology and Physical Medicine (BCPM)
Author 光延 文裕|
Publication Title Journal of Okayama Medical Association
Published Date 2019-12-02
Volume volume131
Issue issue3
Start Page 171
End Page 172
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.131.171
language 日本語
Copyright Holders Copyright (c) 2019 岡山医学会
File Version publisher
DOI 10.4044/joma.131.171
NAID 130007782622
Author 光延 文裕|
Published Date 1988-03-31
Publication Title
Content Type Thesis or Dissertation
Author Mitsunobu, Fumihiro|
Published Date 1988
Publication Title 岡山医学会雑誌
Volume volume100
Issue issue5-6
Content Type Journal Article
JaLCDOI 10.18926/15167
Title Alternative A case of rheumatoid arthritis with hypoproteinemia probably induced by diseasemodifying antirheumatic drug, D-Penicillamine
FullText URL 062_080_083.pdf
Author Kitani, Hikaru| Mitsunobu, Fumihiro| Mifune, Takashi| Okazaki, Morihiro| Tanizaki, Yoshiro|
Abstract 症例は52歳女性で,慢性関節リウマチ(RA)はclassical,stageIV, class 2であった。症状は進行性で加療を行うも改善がみられなかった。平成元年11月RA症状の増悪のための再入院後,Penicillamine 100~200 mg,Sulfasalazine 500mgを合せて投与を行ったところ,血沈,CRP等の検査所見は改善傾向を示したが入院時には正常値であった血清蛋白量がその後5.1g/dlまで低下し,下肢浮腫が出現,その後さらに血清蛋白量は4.1g/dlにまで減少した。治療により蛋白量は5.8g/dlにまで回復したが,低蛋白血症の原因としてはD-Penicillamineの関与が疑われた。
Abstract Alternative A patient with classical rheumatoid arthritis was treated with D-Penicillamine and other drugs. In the course of treatment, the episodes of hypoproteinemia were found twice. The first hypoproteinemia was improved almostly by supportive therapy and withdrawl of administration of medicines, including D-Penicillamine. The second hypoproteinemia was severe and resistant to the treatment. It was suggested that the agent eliciting hypoproteinemia in this case might be D-Penicillamine.
Keywords 慢性関節リウマチ (Rheumatoid arthritis) 低蛋白血症 (Hypoproteinemia) D-ペニシラミン (D-Penicittamine) 抗リウマチ剤 (Disease-modifying antirheumatic drug)
Publication Title 環境病態研報告
Published Date 1991-08
Volume volume62
Start Page 80
End Page 83
ISSN 0913-3771
language 日本語
File Version publisher
NAID 120002307840
Author Takata, Shingo| Ashida, Kozo| Hosaki, Yasuhiro| Hamada, Masanori| Iwagaki, Naofumi| Kikuchi, Hiroshi| Mitsunobu, Fumihiro|
Published Date 2008-03-01
Publication Title 岡大三朝医療センター研究報告
Volume volume76
Content Type Departmental Bulletin Paper
JaLCDOI 10.18926/14987
Title Alternative Clinical effect of spa therapy on lumbargo
FullText URL 068_051_058.pdf
Author Okamoto, Makoto| Ashida, Kozo| Yamamoto, Kazuhiko| Iwagaki, Naofumi| Tsugeno, Hirofumi| Hosaki, Yasuhiro| Mifune, Takashi| Mitsunobu, Fumihiro| Tanizaki, Yoshiro| Tada, Shinya| Harada, Mine|
Abstract 腰痛症患者12例を対象に温泉療法の臨床効果について検討した。臨床効果の判定は,日本整形外科学会の腰痛治療成績判定基準に基づき,自覚症状,他覚症状,及び日常生活動作などの項目を中心に,治療前後で比較検討した。その結果,自覚症状,日常生活動作,総計では,治療前に比べ治療後に有意の改善がみられた。また改善指数や改善率での検討でも温泉療法の有効性が示唆された。年齢別(60才以上と60才未満),入院期間(80日以上と80日未満)別の 検討では,65才未満の症例,80日以上の入院の症例において,改善指数,改善率が,有意差はみられなかったもののより高い傾向がみられた。
Abstract Alternative Clinical effect of spa therapy was evaluated in 12 patients with lumbargo by a scoring system based on the standard judgement of therapy for lumbargo by Japanese Society of Orthopedics. The score for each category of subjective symptoms, objective symptoms, daily life activity, and disorder of urinary bladder, and total score calculated from each score were compared before and after spa therapy. A significant improvement of subjective symptoms, daily life activity, and total score was observed after spa therapy. However objective symptom was not significantly improved. The effects of spa therapy was larger in patients under age of 65, and in those who had long-term spa therapy more than 80 days during their admission. The results suggest that spa therapy IS effective for patients with lumbargo.
Keywords 腰痛症 (lumbargo) 温泉療法 (spa therapy) 腰痛治療判定基準 (scoring system based on the standard judgement of therapy for lumbargo)
Publication Title 岡大三朝分院研究報告
Published Date 1997-12
Volume volume68
Start Page 51
End Page 58
ISSN 0918-7839
language 日本語
File Version publisher
NAID 120002308321
JaLCDOI 10.18926/14842
Title Alternative The relationship between the magnetic resonance imaging of the lumbar spine and lowback pain
FullText URL 72_066_070.pdf
Author Takata, Shingo| Yokoi, Tadashi| Nishida, Norikazu| Okamoto, Makoto| Tsugeno, Hirofumi| Ashida, Kozo| Hosaki, Yasuhiro| Mifune, Takashi| Mitsunobu, Fumihiro| Tanizaki, Yoshiro| Niiya, Kenji| Tanimoto, Mitsune|
Abstract (目的) MRlは腰痛をきたす疾患の診断に必須な検査法である。腰痛と腰椎MRl所見との関係を明らかにすることを目的として検討した。(対象と方法)腰痛を訴えた30例を対象とし、腰椎MRl所見の頻度を調査した。全例に温泉療法を施行した。  (結果)全症例において腰椎MRl上異常所見を認めた。少なくとも1つ以上の椎間板の変性病変をもつ症例は30例中27例(90% )で、椎間板変性はL4/5levelで最も多く認められた(30例中18例)。椎間板ヘルニア を示す症例は30例中10例(33.3% )であった。神経根圧迫を持つ症例は30例中8例(26.7% )であった。腰椎圧迫骨折を持つ症例は30例中6例(20% )であった。温泉療法により腰痛が改善した症例は30例中17例(56.7% )であった。  (結論)腰痛症患者は腰椎MR止異常所見を有した。温泉療法により腰痛の改善を認めたので、MRL上で認めた形態学的異常は必ずしも機能的異常や症状に直結しないと思われた。
Abstract Alternative (Purpose) Magnetic resonance imaging (MRI) is essential to diagnosis of diseases which happen low back pain. The purpose of this study was to investigate the relationship between low back pain and the characteristics on MRI scans of the lumbar spine. (Materials and Methods) We performed MRI examinations of lumbar spine in 30 patients with low back pain and examined the prevalence of abnormal findings on MRI scans of the lumbar spine in 30 patients with low back pain. (Results) Overall in present study, all patients with low back pain had abnormalities around the lumbar spines on MRI. Disc degeneration was present in one or more lumbar levels in 27 (90% ) of all the subjects. The disc degeneration was most commonly observed at U/LS, where 18 (60% ) of all the subjects displayed evidence of disc degeneration. Disc herniation was found in 10 (33.3% ) of all the subjects. Nerve root compression at one level or more was observed in 8 (26.7% ) of the subjects. Compression fracture at one level or more was observed in 6 (20% ) of all the subjects. Spa therapy improved low back pain in 17 (56. 7% ) of the subjects. (Conclusion) All patients with low back pain had abnormalities around the lumbar spines on MRI. Because spa therapy improved low back pain, morphological abnormalities on MRI scans don't always connect with functional abnormalities and symptoms.
Keywords 腰痛症 (Disc disease) MRl (Magnetic resonance imaglng) 椎間板変性 (Lumbar spine)
Publication Title 岡大三朝分院研究報告
Published Date 2002-02-01
Volume volume72
Start Page 66
End Page 70
ISSN 0918-7839
language 日本語
File Version publisher
NAID 120002308103