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ID 629
Eprint ID
629
FullText URL
Title Alternative
ラッテの血清成分の濃度に対するGoitrogenの効果
Author
Djagra, Ida Bagus
Wada, Hiroshi
Abstract
The research was carried out to study the serum concentrations of blood components in the hypothyroidism, using the Wister strain rats. As a goitrogen, methylthiouracil (methiocil; 6-methy I -2-thiouracil) was used. The compound was suspended in 2% of aqueous sol of carboxymethyl cellulose and the suspension was injected into the stomach or injected subcutaneously. In one experiment, the goitrogen disolved partially in aqueous solution of sodium hydroxide was injected subcutaneously to the rats. The period of administration was 12 hours (4 times of injection, 3 hours interval) or of approximately one week, twice injection a day. The blood was taken at 3 hours following the final administration, and serum of the blood was determined for total protein(TP), albumin(Alb), globulin(Gl), glucose(Glu), blood ureal nitrogen(BUN), cholesterol(Chol), Calcium(Ca), magnesium(Mg), and phosphorus(P). By the administration of the goitrogen, serum concentrations of BUN, Chol, Mg increased and that of P decreased. Ratio of Alb/Gl in the serum concentration also was high in the group treated with methiocil in comparison with the control group. Oral treatment of methiocil increased only glycine among amino acids in the serum. The changes of concentration of blood serum component following the administration of goitrogen indicates that steer producing the beef with high degree of fat deposit is in a state of hypothyroidism.
Published Date
1982
Publication Title
岡山大学農学部学術報告
Publication Title Alternative
Scientific Reports of the Faculty of Agriculture Okayama University
Volume
volume59
Issue
issue1
Publisher
岡山大学農学部
Publisher Alternative
Faculty of Agriculture, Okayama University
Start Page
57
End Page
62
ISSN
0474-0254
NCID
AN00033029
Content Type
Departmental Bulletin Paper
language
英語
File Version
publisher
Refereed
False
Eprints Journal Name
srfa