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ID 13984
Eprint ID
13984
FullText URL
Thumnail 106_199.pdf 581 KB
Title Alternative
Studies on the effect of chemotherapy for multiple myeloma with analysis of bone lesion Part 2. Examination of bone status in multiple myeloma
Author
Izumi, Ken
Abstract
Bone status is the most important finding in multiple myeloma. The changes in the bone were examined by various methods such as elcation test, bone x-ray, bone scintigraphy, urine hydroxyproline and quantitative bone mineral by computed tomography (QCT). The elcation test was evaluated in 87 patients with multiple myeloma and 15 with osteopor-osis. The maximum value of hypocalcemia induced by elcatonin was ≧0.25 mmol/L which was considered as an abnormal response compared with the mormal response. The elcationin test is related to the prevailing rate of osteoclastic bone resorption. Myeloma patients with advanced bone disease (multiple lytic lesion, Mixed type) had a higher abnormal response such as hypercalcemia, hyper ALP, hot of the bone status, urine hydroxproline and decrease in the bone mineral then myeloma patients with slight bone disease (diffuse proliferation type). Moreover, the elcation test can indicate whether the durg will be effective in the hyper calcemia. We conclude that the elcation test is important in the evaluation of the bone resorption as a simple test for the prognosis and followed up the skeletal disease in the patients with multiple myeloma.
Keywords
多発性骨髄腫
骨状態
骨塩量
エルカトニン負荷試験
ハイドロキシプロリン
Note
原著
Published Date
1994
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume106
Issue
issue3-4
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
199
End Page
209
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/106/3-4/106_3-4_199/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma