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Title Alternative
The cardiovascular system and catecholamine concentration in blood during simple deep hypothermia with high dose fentanyl
Author
Wake, Mikiko
Abstract
Six adult dogs were anesthetized by deep hypothermia with a combination high dose fentanyl and PGE1 (F group). The circulatory system and blood catecholamine concentration were determined. Another 6 adult dogs were anesthetized by deep hypothermia with a combination ether and PEG1 (E group) for a comparison with the F group. Before cooling under anesthesia, the PAP, PVRI and Pp/Ps showed a significant difference in the E group. During cooling, the MAP was 74% and 56% of the control values in the F and E groups, respectively and there were significant differences between the F and E groups. The peak dp/dt/IP was significantly different between the F and E groups at the lowest temperature (46% and 27% of the conrol values, respectively). The CI was 34% and 25% of control values at the lowest temperature in both groups. EP or NE did not significantly increase during cooling or rewarming in the F group. The EP had a tendency to increase during rewarming and NE significantly increased in comparison with the control values during cooling and warming in the E group. Combination anesthesia with high dose fentanyl and PGE1 inhibits the circulatory systems to a lesser degree, resulting in easier maintenance of the circulatory system. This combination system is also more stable than that with ether and PGE1 or with ether and TFP.
Keywords
大量フェンタニール
単純超低体温麻酔
循環動態
血中カテコラミン濃度
Published Date
1990-04
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume102
Issue
issue3-4
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
435
End Page
452
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/102/3-4/102_3-4_435/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma