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ID 18322
Eprint ID
18322
FullText URL
Thumnail 77_1017.pdf 394 KB
Title Alternative
Studies on the Physiological Factors Participating on the Biosynthesis of Pyocianine by Pseudomonas aeruginosa
Author
Sakano, Saizo
Abstract
Pseudomonas aeruginosa produces the two pigments, namely Pyocianine and Fluorescin. The Pyocianine is bluish green pigment and is derivative of phenazine pigment. In this paper, the physiological factors that give influences on the biosynthesis of Pyocianine by Pseudomouas aeruginosa in culture will be presented. 1. Pseudomonas aeruginosa required glycerine as a nitrogene source for the biosynthesis of Pyocianine. In a case that glucose was used as carbon source, the addition of magnesium ion was essential. 2. Within alanine, glutamate and aspartate on which the author examined, only alanine was of effective as nitrogen source for the Pyocianine synthesis. 3. The following results have been investigated by the studies on the atmospheric condition. Pseudomonas aeruginosa produced the pigment at a aerobic condition in the chemically satisfactory culture media, but could not produce at anaerobic condition in any culture media. 4. In the acidic media below pH 6.0, the growing of bacteria was very slight and the Pyocianine could not be produced. Moreover, the pigment did not be synthesized when the pH was descended rapidly, even if the startiag pH of the medium was neutral or slight basic. 5. The growing of the bacteria is indispensable for the synthesis of Pyocianine, then the resting cells could not synthesize the pigment.
Published Date
1965-07-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume77
Issue
issue7
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
1017
End Page
1023
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/77/7/77_7_1017/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma