JaLCDOI 10.18926/40427
Title Alternative INDICE DE NUTRITION AND OXIDATIOM-REDUCTION POTENIAL OF MINERAL WATERS
FullText URL pitsr_012_015_020.pdf
Author Oshima, Yoshio|
Abstract Indice de nutrition (Pech), indice de nutrition simplifié (Rimattei), membrane potential difference of human skin, and oxidation-reduction potential of several mineral watem were measured. Their balneological significance was discussed.
Publication Title 岡山大学温泉研究所報告
Published Date 1953-09
Volume volume12
Start Page 15
End Page 20
ISSN 0369-7142
language 日本語
File Version publisher
NAID 120002509304
JaLCDOI 10.18926/40405
Title Alternative EFFECT OF THE INTERNAL USE OF MISASA (RADON SPRING), HAMAMURA (SULFATED CALCIUM SPRING) AND TOTTORI (SULFATED MURIATED SPRING) SPRING WATERS UPON THE ALIMENTARY HYPERGLYCAEMIA IN RABBITS
FullText URL pitsr_010_013_016.pdf
Author Oshima, Yoshio|
Abstract Five years ago Morinaga reported that the intemal use of the thermal waters of Misasa promoted the action of insuline, inhibited the adrenaline hyperglycaemia and suppressed the alimentary hyperglycaemia. But the highest radon content of the waters used at that time was about 1000×10(-10) Curie units per liter. Recently a more highly radioactive spring was found in Misasa, its radon content being 3000-4000×l0(-10) Curie units per liter, though very feebly mineralized (under 0.5 g per liter) and cold. Therefore the hypoglycaemic effect of this newly discovered water was, investigated in rabbits and compared with the effects of two other thermal waters in Tottori Prefecture and of plain water as a control. Twenty cc. of ten per cent glucofoe solution in thermal waters or in plain water per kilogram of bodyweight was administered to the rabitts by stomach tube and blood sugar level was determined before, 30, 60, 120, and 180 minutes after the administration. All of the three thermal waters decreased the glycaemia significantly as compared the results with plain water control.
Publication Title 岡山大学温泉研究所報告
Published Date 1953-03
Volume volume10
Start Page 13
End Page 16
ISSN 0369-7142
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/40400
language 日本語
File Version publisher
NAID 120002509293
JaLCDOI 10.18926/40361
Title Alternative Studies of the radio-active springs. XXV The effect of Thoron spring bath on Rotter's reaction
FullText URL rbl_003_018_020.pdf
Author Oshima, Yoshio|
Abstract In the preliminary papers the author reported that the Thoron in thermal water passes throngh the skin and stimulates the subcutaneous connective tissue cells. Sotozono proved that the reduced ascorbic acid content in the blood increases after the Radonspring bath. Before and after thermal bath the author measured the time necessary for the complete decoloration of intradermally injected dichlorphenol-indophenol solution. Compared with the plain water bath at a same temperature, the Thoron spring bath seems to have a tendency to reduce the time necessary for the decoloration.
Publication Title 放射能泉研究所報告
Published Date 1950-07-25
Volume volume3
Start Page 18
End Page 20
language 日本語
File Version publisher
NAID 120002484885
JaLCDOI 10.18926/40359
Title Alternative Studies of the radio-active springs (XXII-XXIII)
FullText URL rbl_003_011_014.pdf
Author Oshima, Yoshio|
Publication Title 放射能泉研究所報告
Published Date 1950-07-25
Volume volume3
Start Page 11
End Page 14
language 日本語
File Version publisher
NAID 120002484883
JaLCDOI 10.18926/40348
Title Alternative MEDICAL STUDIES ON CHONDROITIN SULFATE (III)
FullText URL 013_036_041.pdf
Author Oshima, Yoshio| Sotozono, Masazumi|
Abstract 2-5cc. of 1% Rodium chondroitin-sulfate solution subcutaneouRly or 2cc. of 5% solution intraveneously was administered to 37 cares of painful disorders such as headache, backache or arthralgia. A marked improvement was obtained in 12 cares and a moderate result was seen in 16 cases. No definite change was proved concerning blood pressure in the patients and detoxicating effect in animal experiment.
Publication Title 岡山大学温泉研究所報告
Published Date 1953-12
Volume volume13
Start Page 36
End Page 41
ISSN 0369-7142
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/40340
language 日本語
File Version publisher
NAID 40017532453
JaLCDOI 10.18926/40344
Title Alternative STUDIES ON VITRIOL SPRINGS (4) ON THE COPPER, ZINC, NICKEL, AND COBALT CONTENTS OF BLOOD AFTER THE INTERNAL USE OF A VITRIOL WATER
FullText URL 013_015_017.pdf
Author Oshima, Yoshio| Ashizawa, Takashi|
Abstract Sotozono proved that the administration of daily 20cc of Fujino Mineral Water (an acid vitriol water containing copper, zinc, nickel and cobalt) has a remarkably beneficial effect on several kinds of hypochromic anemia. It contains 9.56gms of iron, 0.007gm of zinc, 0.005gm of copper 0.001gm of nickel, and 0.006gm of cobalt in one liter. 20 - 40cc of Fujino water was diluted 5 - 10 fold with plain water and administered to the fasting patients perorally. Blood samples were taken from cubital vein before, 1, 2, 4, 6, 24, 48, and 72 hours after the intake of the vitriol water. Copper, zinc, nickel and cobalt contents of the blood samples were measured by Ashizawa' s dithizone- chromatographic method. It was shown that copper, nickel, and cobalt contents of blood rose unexpectedly high temporarily, in a manner that did not correspond to their amount in the given mineral water. So that the mobilization of copper, nickel, and cobalt in the body after the intake of the mineral IVrter was susrected. Zinc content of blood showed no constant tendency.
Publication Title 岡山大学温泉研究所報告
Published Date 1953-12
Volume volume13
Start Page 15
End Page 17
ISSN 0369-7142
language 日本語
File Version publisher
NAID 120002484879
JaLCDOI 10.18926/40324
Title Alternative RADON CONTENT OF HOT SPRINGS IN TOTTORI PREFECTURE, JAPAN
FullText URL 014_001_014.pdf
Author Oshima, Yoshio| Yamada, Naoharu| Mifune, Masaaki|
Abstract 1. Radon content of 166 thermal waters in IWAI, TOTTORI YOSHIOKA, HAMAMURA, TOGO, SEKIGANE, MISASA, and KAlKE Hot Springs was measured by I. M. Fontactoscope in the years 1950-1951. Of which 66 samples showed a radon content over 30×10(-10) curie units per liter. Namely, 50 springs in Misasa, 6 in Sekigane, 9 in Hamamura, and one in Togo belonged to the radioactive spring in the definition by Ministry of Social Welfare. The highest Radon content (1150×10(10) curie units per liter) was recorded in Hisuino-Yu in Misasa, where five springs had a radon content over 360×10(-10) curie units per liter. 2. No marked difference was proved between the results obtained this time and the data in the former reports concerning the radon content of these thermal springs. 3. Radon content proved higher in the springs which issue from granite than in the springs of other districts. No definite relation was proved between the radon content and water temperature. The radon content was generally high in simple thermals or in weak sodium chloride springs, low in sulfated springs and in saline springs which had a comparatively high sulfate content.
Publication Title 岡山大学温泉研究所報告
Published Date 1954-03
Volume volume14
Start Page 1
End Page 14
ISSN 0369-7142
language 日本語
File Version publisher
NAID 40017532457
JaLCDOI 10.18926/40319
Title Alternative REPORT OF THE CHEMICAL ANALYSIS OF MISASA HOT SPRINGS, TOTTORI PREFECTURE
FullText URL 016_001_018.pdf
Author Oshima, Yoshio| Mifune, Masaaki| Yamada, Naoharu| Ueyama, Akiko|
Abstract The water samples of 55 springs of Misasa were analysed in the years 1950~1951. The temperatures of the waters ranged from 44° to 85° C. Radon content ranged from 34.1 to 2360×10(-10) curies per liter. pH 6.2~7.5. Evaporation residue: 534~1940 mg/kg. K(+) :10.4~47.3mg/kg. Na(+) : 140.4~574mg/kg. Ca(2+) : 7.56~49.06mg/kg. Mg(2+) : 0.11~15.3mg/kg.. Fe(2+) : 0.10~0.67mg/kg. Cl(-) : 138~854mg/kg. SO(4)(2-) : 29.2~187mg/kg. HCO(3)(-) : 74.8~370mg/kg. HBO(2)(-) : 1.80~19.6mg/kg. S(2)O(3)(2-) : o.62~3.69mg/kg. Radon sources seem to exist at shallow places under the ground and the radon in the thermal wacer is supposed to have been derive partly from the ground water which also contains considerable amount of radon. A close linear correlation (r=0.751) was proved between the sulfate and the chloride ion contents.
Publication Title 岡山大学温泉研究所報告
Published Date 1956-01
Volume volume16
Start Page 1
End Page 18
ISSN 0369-7142
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/40318
language 日本語
File Version publisher
NAID 40017532473
JaLCDOI 10.18926/19595
Title Alternative MEDICAL STUDIES ON CHONDROITIN SULFATE (2nd Report)
FullText URL 007_020_025.pdf
Author Oshima, Yoshio| Yokota, Takeo|
Abstract After the internal use of daily 3 grams of crude chondroitin sulfate cholinesterase activity of serum decreased and elimination of glycuronic acid in urine increased, but no definite change in serum mucoprotein level was observed. Mucoprotein in serum showed a positive linear correlation to erythrocyte sedimentation rate, and chondroitin sulfate promoted the e.s.r. in vitro and in vivo. Chondroitin sulfate showed no marked influence on phagocytosis of human leucocytes in vitro, but it promoted the production of agglutinin in rabbits by subcutaneous injection.
Publication Title 岡山大学温泉研究所報告
Published Date 1952-08
Volume volume7
Start Page 20
End Page 25
ISSN 0369-7142
language 日本語
File Version publisher
NAID 40017532418
JaLCDOI 10.18926/19583
Title Alternative BALNEOLOGICAL STUDIES USING RADIO-ACTIVE ISOTOPES (1) ON THE MECHANISM OF THE ACTION OF SODIUM SULFATE SPRING BATH.
FullText URL 007_001_005.pdf
Author Oshima, Yoshio| Yokota, Takeo|
Abstract Using Na(2)SO(4) labelled with S(35) transition of sulfate ion into the body across the skin was investigated soon after the bath in sodium sulfate solution at varying conditions. Mice were used as test animal. Percutaneous absorption of sulfate ion proved to be promoted at high bath temperature (45℃) than at indifferent temperature(37℃). stronger by the bath of longer duration (30min.) than by the bath of shorter duration (10min.), increased after repeated baths than after a single bath. It was accelerated by making a burn to the skin of the bathed animals. Layton and Dziewiatkowski proved that the parenterally administered sulfate ion was partly fixed in the connective tissue as chondroitin sulfate. The author had proved that chondroitin sulfate relieves pain, increases peripheral circulation and when administered parenterally promotes production of immune bodies. In Japan natural and artificial Glauber's salt spring bath are known to have a beneficial effect on wound healing, but no satisfactory explanation was given till today. Lith reported that a hypertonic solution of sodium sulfate promoten wound cure by external application and Seki showed that subcutaneous connective tissue of mice was stimulated by the bath in sodium sulfate spring. And so the abovementioned author's data seem to throw some light on solving the problem.
Publication Title 岡山大学温泉研究所報告
Published Date 1952-08
Volume volume7
Start Page 1
End Page 5
ISSN 0369-7142
language 日本語
File Version publisher
NAID 120002309061
JaLCDOI 10.18926/15594
Title Alternative STUDIES ON SERUM MUCOPROTEIN (1) SERUM MUCOPROTEIN LEVEL IN NORMAL AND PATHOLOGICAL STATES OF JAPANESE.
FullText URL 008_001_007.pdf
Author Oshima, Yoshio| Ueda, Yoshio|
Abstract Serum mucoprotein level in 16 normnls and 3CO cases of diseased was investignted by Winzler' s method. Using biuret rengent normal range of serum mucoprotein proved to be 94-120mg per cent. Higher mucoprotein content was often recognized in rheumatoid arthritis, cancer, pneumonia, and hepatitis. High mucoprotein level in cancer or ulcer patients was decrensed after their resection. A positive linear correlation wns shown between erythrocytes sedimentation rate and mucoprotein level in serum. But no close relation was observed between serum mucoprotein and Takata reaction, Wassermann reaction or total protein content in serum.
Publication Title 岡山大学温泉研究所報告
Published Date 1952-11
Volume volume8
Start Page 1
End Page 7
ISSN 0369-7142
Related Url http://eprints.lib.okayama-u.ac.jp/15355
language 日本語
File Version publisher
NAID 40017532505
JaLCDOI 10.18926/15589
Title Alternative MEDICAL STUDIES ON CHONDROITIN SULFATE (1)
FullText URL 006_052_061.pdf
Author Oshima, Yoshio|
Abstract Chondroitin sulfate (daily 3g. per os) was administered to fifty cases of painful disorders, such as hemicrania, neuralgia, chronic rheumatoid arthritis, perialthritis, etc. And amelioration was observed in 34 cases (68%). Chondroitin Sulfate promotes the blood clotting time by intravenous injection, but has no influence on blood viscosity. It inhibits the action of cholin esterase slightly in vitro and shows a tendency to increase peripheral circulation by Laewen-Trendelenburgs method. It showed no definite effect on blood pressure in the above-mentioned patients. By Magnus method it was shown that chondroitin sulfate accelerates the motility of the isolated rabbit intestine and suppresses the action of adrenalin. Chondroitin sulfate increases the permeability of tissue, but it shows a slight inhibitory action on testicular byaluronidase. Peroral administration of chondroitin sulfate promotes diuresis, increases the elimination of total sulfate and diminishes the neutral sulfur in the urine.
Publication Title 岡山大学温泉研究所報告
Published Date 1952-03
Volume volume6
Start Page 52
End Page 61
ISSN 0369-7142
language 日本語
File Version publisher
NAID 40017532411
JaLCDOI 10.18926/15584
Title Alternative SENSITIVITY TO HISTAMINE DURING A SERIES OF THERMAL BATHS.
FullText URL 006_049_051.pdf
Author Oshima, Yoshio| Yokota, Takeo|
Abstract Sensitivity of mice to histamine was estimated with the death-rate by its subcutaneous injection. In control group without bath ten mg. of histamine per ten g. of body weight proved to be tolerable, but twenty mg. of histamine per ten g. of body weight was lethal in August. To 24 mice were given everyday a plain water bath at 37℃ for ten minutes. To another 24 mice were given everyday a thermal bath of Misasa at 37℃for ten minutes. On the 4th, 7th, 14th and 21st day to each six mice of both groups was given a subcutaneous injection of histamine, namely to three mice was given ten mg. of histamine per ten g. of bodyweight and to another three mice was given twenty mg. of histamine per ten g. of body weight. In plain water bath group no change in death rate was shown during the series of bath days. But in the thermal bath group a 100% 1ethality was recognized on the 4th day, 67% lethality was proved on the 7th day and only 17% lethality was shown on the 14th day. Histamine or histaminelike substance is known to be a chemical agent liberated in the skin by any skin irritants. And the above-mentioned change in the sensitivity to histamine during a series of thermal baths suggests an explanation to the mechanism of thermal crisis that has a tendency to occur in the first week of thermal bath cure.
Publication Title 岡山大学温泉研究所報告
Published Date 1952-03
Volume volume6
Start Page 49
End Page 51
ISSN 0369-7142
language 日本語
File Version publisher
NAID 120002307862
JaLCDOI 10.18926/15581
Title Alternative SEASONAL DIFFERENCE IN THE EFFECT OF THERMAL BATH ON BLOOD CATALASE.
FullText URL 006_046_048.pdf
Author Oshima, Yoshio|
Abstract Blood catalase level in healthy rabbits was measured before and after thermal bath of Misasa in January, May, July and September. And the differences in the effect of thermal bath between the four seasons were investigated. Blood catalase level in rabbits proved to be highest in winter and lowest in September. A slight fall in blood catalase level was recognized an hour after the thermal bath at 42℃ for five minutes. And in September the degree of fall seemed to be slightest and the recovery soonest.
Publication Title 岡山大学温泉研究所報告
Published Date 1952-03
Volume volume6
Start Page 46
End Page 48
ISSN 0369-7142
language 日本語
File Version publisher
NAID 120002307946
JaLCDOI 10.18926/15531
Title Alternative STUDIES ON VITRIOL SPRINGS,(8) BLOOD CATALASE LEVEL AFTER THE INTERNAL USE oF VITRIOL WATERS.
FullText URL 005_057_058.pdf
Author Oshima, Yoshio|
Abstract After the internal use of 20-40 cc of Fujino or Yanahara mineral waters a rise in the iron, copper, nickel and cobalt content in blood and a slight fall in the bloodcatalase level were observed. No significant difference was proved between the effects of two vitriol waters.
Publication Title 岡山大学温泉研究所報告
Published Date 1951-08
Volume volume5
Start Page 57
End Page 58
ISSN 0369-7142
Related Url http://eprints.lib.okayama-u.ac.jp/15926
language 日本語
File Version publisher
NAID 120002307329
JaLCDOI 10.18926/15530
Title Alternative STUDIES ON VITRIOL SPRINGS,(7) IN-VITRO EFFECT OF VIIRIOl WATERS ON OXIDOREDUCTASE.
FullText URL 005_055_056.pdf
Author Oshima, Yoshio|
Abstract Fujino and Yanahara spring waters were used. The latter, is the strongest copper spring in Japan. Iron ion in Fujino mineral water is mainly ferric and in Yanahara mineral water mainly ferrous. Yanahara spring water promotes the action of oxidoreductase in milk and liver extract. It also promotes the action of succinic dehydrase in albino rat muscle. And this promoting action of spring water is inhibited by cyanide. Fujino is less active than Yanahara and Mitsuishi proved to be almost inactive.
Publication Title 岡山大学温泉研究所報告
Published Date 1951-08
Volume volume5
Start Page 55
End Page 56
ISSN 0369-7142
Related Url http://eprints.lib.okayama-u.ac.jp/15926
language 日本語
File Version publisher
NAID 120002307811
JaLCDOI 10.18926/15525
Title Alternative THE MEMBRANE POTENTlAL OF THE LIVING HUMAN SKIN AND THE MINERALWATERS
FullText URL 004_049_053.pdf
Author Oshima, Yoshio|
Abstract The membrane potential difference with the living human skin between the physiological saline and the mineral waters was measured. The hypotonic mineral waters, that have a pH higher than the isoelectric point of human epidermis, showed a positive potential against the physiological saline. The membrane potential difference of these mineral waters against the physiological saline at the same temperature tends to increase by raising the water temperature. The acid waters showed either a positive or a negative potential against the physiological saline. The membrane potential difference between the mineral wates at room temperature and at the temperature raised above it is increased according to their temperature difference,
Publication Title 放射能泉研究所報告
Published Date 1951-03
Volume volume4
Start Page 49
End Page 53
language 日本語
File Version publisher
NAID 120002307611
JaLCDOI 10.18926/15522
Title Alternative STUDIES OF THE RADIO-ACTIVE SPRINGS (XXV-XXVII)
FullText URL 004_013_023.pdf
Author Oshima, Yoshio|
Publication Title 放射能泉研究所報告
Published Date 1951-03
Volume volume4
Start Page 13
End Page 23
language 日本語
File Version publisher
NAID 120002307917