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ID 16348
Eprint ID
16348
FullText URL
Thumnail 95_711.pdf 424 KB
Title Alternative
Studies on cell-mediated immunity in patients with malignant tumor. Part 1. Leukocyte migration inhibition test in patients with lung cancer.
Author
Terao, Seiya
Abstract
Leukocyte migration inhibition tests (LMIT) were performed in 46 patients with primary lung cancer. The three kinds of antigens were allogeneic 3 M KCl extracts of lung cancer tissues obtained from patients with adenocarcinoma, squamous cell carcinoma and small cell carcinoma. Nine of the 46 patients (19%) had positive LMITs using adenocarcinoma antigen, seven patients (15%) with squamous cell carcinoma antigen and eleven patients (24%) with samll cell carcinoma antigen. LMITs were all negative in 10 patients with benign lung disease, 10 patients with non-pulmonary cancer and 12 healthy volunteers. These findings suggested that some patients with lung cancer had cell-mediated immunity against a lung tumor-associated antigen not restricted to a given histologic type of lung cancer. Further study on the relationship between LMIT and the clinical stage of lung cancer revealed that the percentage of positive LMITs in patients with localized disease was higher than in patients with extensive disease.
Keywords
leukocyte migration inhibition test
primary lung cancer
3 M KCl extracts
Published Date
1983-08-31
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume95
Issue
issue7-8
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
711
End Page
719
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/95/7-8/95_7-8_711/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma