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ID 30885
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Author
Wakiguchi, Hiroshi
Fujieda, Mikiya
Kubota, Haruo
Matsumoto, Kenji
Wakiguchi, Akiko
Kurashige, Takanobu
Abstract

Anti-Epstein-Barr virus (EBV) antibodies were tested in 11 children with chronic active EBV infection. Anti-virus capsid antigen (VCA)-IgG antibody titers ranged from 1:640 to 1:10,240. Anti-VCA-IgM antibody was consistently positive in 5 of the 11 patients; anti-VCA-IgA antibody was consistently positive in 6 of the 10 patients; anti-early antigen (EA)-IgG antibody was consistently positive in 10 of the 11 patients and anti-EA-IgA antibody was consistently positive in 4 out of the 7 patients. Anti-EBV nuclear antigen (EBNA) antibody was not detected in two patients. Consistently positive anti-VCA-IgA- and anti-EA-IgA- antibody may be a characteristic feature of abnormal antibody responses in severe chronic active EBV-infection in childhood.

Keywords
IgA antibody
Epstein-Barr virus
chronic active EBV-infection
Amo Type
Article
Published Date
1989-06
Publication Title
Acta Medica Okayama
Volume
volume43
Issue
issue3
Publisher
Okayama University Medical School
Start Page
193
End Page
196
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
英語
File Version
publisher
Refereed
True
PubMed ID
Web of Sience KeyUT