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ID 53679
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Author
Hagiya, Hideharu
Iwamuro, Masaya ORCID Kakenhi
Tanaka, Takehiro Kakenhi
Hanayama, Yoshihisa
Otsuka, Fumio ORCID Kakenhi
Abstract
A 60-year-old woman with rheumatoid arthritis treated with methotrexate for a decade complained of slight epigastric discomfort. A positive cytomegalovirus (CMV) antigenemia test indicated the probability of CMV-related gastrointestinal infection, for which esophagogastroduodenoscopy was performed. Endoscopic findings showed a non-specific duodenal mucosal lesion;however, pathological investigation revealed evidence of CMV duodenitis. There is scarce information on the clinical and pathological features of CMV-related duodenitis, likely due to its low prevalence. CMV infection in the upper gastrointestinal tract should be considered as a differential diagnosis in high-risk individuals, particularly those with symptoms relating to the digestive system. Biopsy examinations are preferable for the definitive diagnosis of CMV gastrointestinal infection, even without specific endoscopic features.
Keywords
antigenemia
cytomegalovirus (CMV)
gastrointestinal infection
methotrexate
opportunistic infection
Amo Type
Case Report
Published Date
2015-10
Publication Title
Acta Medica Okayama
Volume
volume69
Issue
issue5
Publisher
Okayama University Medical School
Start Page
319
End Page
323
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
英語
Copyright Holders
CopyrightⒸ 2015 by Okayama University Medical School
File Version
publisher
Refereed
True
PubMed ID
Web of Science KeyUT