start-ver=1.4
cd-journal=joma
no-vol=60
cd-vols=
no-issue=
article-no=
start-page=31
end-page=34
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1989
dt-pub=198907
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Oxygen inhalation therapy for chronic venous ulcer. -An additional treatment modality-
kn-title=難治な静脈性潰瘍に対する酸素療法 ―補助療法としての意義―
en-subtitle=
kn-subtitle=
en-abstract=Prolonged venous hypertension leads to increase the number of dilated capillaries and to fibrin deposition around them which may form a barrier to the diffusion of oxygen and other nutrients from the blood to the tissue, so that cell death and ulceration may occur. Following inhalation of 100 % -O(2), increased partial pressure of subcutaneous tissue oxygen (pO(2)) around the ulcer was confirmed by means of medical mass spectrometry, which was found comparable to or higher than the level of ulcer-free area (chest) on room air. Four patients suffering from chroriic ulcers were successfully treated by 100 % -O(2) inhalation, 4-5 ℓ/min, for one hour every day in addition to the simpie measures of reducing venous stasis. Suffice it to say that the inhalation of 100 % -O(2) may be applicative to an additional treatment modality in chronic venous ulceration, though inhalation of 100 % -O(2) for a long period of time may not be recommended.
kn-abstract=長期にわたり反復する静脈性潰瘍は，静脈圧亢進により拡張した毛細管の増加とその周辺に滲出したフィブリンの沈着により，血液からの酸素，及び栄養物の供給が妨げられている。医用質量分析装置による皮下組織ガス分圧の評価で経鼻的に100　％　の酸素吸入により潰瘍周辺への酸素供給が認められたので，重篤臨床例に対して静脈圧減圧処置に加えて酸素吸入を併用したところ，潰瘍の治癒傾向は著しく速くなり，補助療法としての意義を認めた。
en-copyright=
kn-copyright=

en-aut-name=KomotoYoshiaki
en-aut-sei=Komoto
en-aut-mei=Yoshiaki
kn-aut-name=古元嘉昭
kn-aut-sei=古元
kn-aut-mei=嘉昭
aut-affil-num=1
ORCID=

en-aut-name=TokunouTeruo
en-aut-sei=Tokunou
en-aut-mei=Teruo
kn-aut-name=得能輝男
kn-aut-sei=得能
kn-aut-mei=輝男
aut-affil-num=2
ORCID=

en-aut-name=SodaMitsuhiro
en-aut-sei=Soda
en-aut-mei=Mitsuhiro
kn-aut-name=曽田益弘
kn-aut-sei=曽田
kn-aut-mei=益弘
aut-affil-num=3
ORCID=

en-aut-name=HiraiShunichi
en-aut-sei=Hirai
en-aut-mei=Shunichi
kn-aut-name=平井俊一
kn-aut-sei=平井
kn-aut-mei=俊一
aut-affil-num=4
ORCID=

en-aut-name=MorisueShinnhachi
en-aut-sei=Morisue
en-aut-mei=Shinnhachi
kn-aut-name=森末真八
kn-aut-sei=森末
kn-aut-mei=真八
aut-affil-num=5
ORCID=

en-aut-name=SuzukaIchio
en-aut-sei=Suzuka
en-aut-mei=Ichio
kn-aut-name=鈴鹿伊智雄
kn-aut-sei=鈴鹿
kn-aut-mei=伊智雄
aut-affil-num=6
ORCID=

en-aut-name=SunakawaMitsuru
en-aut-sei=Sunakawa
en-aut-mei=Mitsuru
kn-aut-name=砂川満
kn-aut-sei=砂川
kn-aut-mei=満
aut-affil-num=7
ORCID=

en-aut-name=YorozuHidenori
en-aut-sei=Yorozu
en-aut-mei=Hidenori
kn-aut-name=萬秀憲
kn-aut-sei=萬
kn-aut-mei=秀憲
aut-affil-num=8
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部付属環境病態研究施設リハビリテーション外科学分野

affil-num=2
en-affil=
kn-affil=岡山大学医学部付属環境病態研究施設リハビリテーション外科学分野

affil-num=3
en-affil=
kn-affil=岡山大学医学部付属環境病態研究施設リハビリテーション外科学分野

affil-num=4
en-affil=
kn-affil=岡山大学医学部付属環境病態研究施設リハビリテーション外科学分野

affil-num=5
en-affil=
kn-affil=岡山大学医学部付属環境病態研究施設リハビリテーション外科学分野

affil-num=6
en-affil=
kn-affil=岡山大学医学部付属環境病態研究施設リハビリテーション外科学分野

affil-num=7
en-affil=
kn-affil=岡山大学医学部付属環境病態研究施設リハビリテーション外科学分野

affil-num=8
en-affil=
kn-affil=岡山大学医学部付属環境病態研究施設リハビリテーション外科学分野
en-keyword=慢性静脈性潰瘍 (Chronic venous ulcer)
kn-keyword=慢性静脈性潰瘍 (Chronic venous ulcer)
en-keyword=組織ガス分圧 (Partial pressure of tissue gases)
kn-keyword=組織ガス分圧 (Partial pressure of tissue gases)
en-keyword=医用質量分析装置 (Medical mass spectrometer)
kn-keyword=医用質量分析装置 (Medical mass spectrometer)
en-keyword=酸素拡散 (Oxygen diffusion)
kn-keyword=酸素拡散 (Oxygen diffusion)
en-keyword=酸素吸入療法 (Oxygen inhalation therapy)
kn-keyword=酸素吸入療法 (Oxygen inhalation therapy)
END