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ID 13366
Eprint ID
13366
FullText URL
Thumnail 118_17.pdf 3.28 MB
Author
武田 昌也
稲垣 兼一
鈴木 二郎
三浦 大志
藤尾 栄起
松原 広己
伊達 洋至
大江 透
槇野 博史
Keywords
原発性肺高血圧症 (PPH)
骨形成蛋白 (BMP)
肺動脈血管平滑筋細胞
TGF-β スーパーファミリー
BMP IB型受容体 (ALK-6)
Note
平成16年度岡山医学会賞(砂田賞)受賞論文
Published Date
2006-05-01
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume118
Issue
issue1
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
17
End Page
21
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/118/1/118_1_17/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
References
1) Nichols WC, Koller DL, Slovis B, Foroud T, Terry VH, Arnold ND, Siemieniak DR, Wheeler L, Phillips JA 3rd, Newman JH, Conneally PM, Ginsburg D, Loyd JE: Localization of the gene for familial primary pulmonary hypertension to chromosome 2q31-32. Nat Genet (1997) 15, 277-280.
2) Deng Z, Morse JH, Slager SL, Cuervo N, Moore KJ, Venetos G, Kalachikov S, Cayanis E, Fischer SG, Barst RJ, Hodge SE, Knowles JA: Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene. Am J Hum Genet (2000) 67, 737-744.
3) Lane KB, Machado RD, Pauciulo MW, Thomson JR, Phillips JA 3 rd, Loyd JE, Nichols WC, Trembath RC: Heterozygous germline mutations in BMPR 2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension. The International PPH Consortium. Nat Genet (2000) 26, 81-84.
4) Thomson JR, Machado RD, Pauciulo MW, Morgan NV, Humbert M, Elliott GC, Ward K, Yacoub M, Mikhail G, Rogers P, Newman J, Wheeler L, Higenbottam T, Gibbs JS, Egan J, Crozier A, Peacock A, Allcock R, Corris P, Loyd JE, Trembath RC, Nichols WC: Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family. J Med Genet (2000) 37, 741-745.
5) Takeda M, Otsuka F, Nakamura K, Inagaki K, Suzuki J, Miura D, Fujio H, Matsubara H, Date H, Ohe T, Makino H: Characterization of the bone morphogenetic protein (BMP) system in human pulmonary arterial smooth muscle cells isolated from a sporadic case of primary pulmonary hypertension: roles of BMP type IB receptor (activin receptor-like kinase-6) in the mitotic action. Endocrinology (2004) 145, 4344-4354.
6) Kouchi H, Nakamura K, Fushimi K, Sakaguchi M, Miyazaki M, Ohe T, Namba M: Manumycin A, inhibitor of ras farnesyltransferase, inhibits proliferation and migration of rat vascular smooth muscle cells. Biochem Biophys Res Commun (1999) 264, 915-920.
7) Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T: Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature (2001) 411, 494-498.
8) Elbashir SM, Lendeckel W, Tuschl T: RNA interference is mediated by 21-and 22-nucleotide RNAs. Genes Dev (2001) 15, 188-200.
language
日本語
OAI-PMH Set
岡山大学
Copyright Holders
Copyright© 岡山医学会
File Version
publisher
Refereed
True
Sort Key
3
Eprints Journal Name
joma