岡山医学会 Acta Medica Okayama 0030-1558 71 5-1 1959 放射線障碍の本態に関する実験的研究 第1編 放射線照射の血球に及ぼす組織化学的変化に就いて 2393 2398 EN Michio Yamamoto Soichi Nishishita Ryo Ando Shigeo Nobuki Izumi Tukamoto Tadasi Hasigami Keiko Akagi Masahiro Wakimoto Koki Yamamoto There are many studies on radiation disturbances but as for the causative factor of the disturbances it is vaguely considered to be the disorders of the hematopoietic organs and still it is uncertain whether such disturbances are due to the primary or the secondary factor, However, in our experiments we have come across the evidence indicating that such disorders can be induced even by an indirect causative factor. Following upon this point, we have studied the problem from histochemical standpoint of blood cells and have clarified that various substances what may be called toxic granules are produced during X-ray irradiation. Therefore, with the purpose to find an aid in the diagnosis of radiation disturbances as well as a clue in the elucidation of the causative factor we performed the present experiment by pursuing the relationship between the radition disturbance and the dosage of X-rays. No potential conflict of interest relevant to this article was reported.