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Title Alternative
Radiosensitivity of an isolated human malignant fibrous histiocytoma cell line
Author
Kawasaki, Shoji
Mizuta, Akifumi
Kashitani, Naoko
Kuroda, Masahiro
Hiraki, Yoshio
Aono, Kaname
Sato, Jiro
Ogino, Tetsuro
Nakanishi, Takashi
Abstract
A human cell line (YU-137) isolated from a bone of malignant fibrous histiocytoma in bone was evaluated using immunofluorescent staining methods. Cell cycle fractions were studied by flow cytometry. The magnitude of G(2)+M fraction in a cell cycle of an exponentially growing population of YU-137 was higher than that observed in HeLa S3 cells. The doubling time of YU-137 cells was 3.2 days. The radiosensitivity of this cell line was compared with HeLa S3 and HMV-1 cells from dose response curves against X-irradiation. The parameters of radiosensitivity of YU-137 against X-irradiation were n=2.0, D(0)=1.05 Gy and D(0)=0.73 Gy. From these data, the radiosensitivity of YU-137 was discussed.
Keywords
Tissue culture
Malignant fibrous histeocytoma
Radiosensitivity
Flow cytometry
Published Date
1989-02
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume101
Issue
issue1-2
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
1
End Page
6
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/101/1-2/101_1-2_1/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma