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ID 41300
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Title Alternative
Spectrophotometric Studies on the Decomposition of Biliubin Part II Studies on the Oxidation of Natural Ester-form Bilirubin by Oxygen in Caustic Soda Solution
Author
Takeuchi, Ryo
Abstract
1. The absorption maximum on the addition of phosphate buffer after the dissolution of ester-form bilirubin into caustic soda solution dasplayed at 410 mμ imediately after the dissolution without the relation of the pH value of solvent and the diazo reaction showed prompt one. 2. Ester-form bilirubin was rapidly destroyed with high pH value in alkaline solution. The velocity of oxidizing decomposition was more rapid than that of crystalline bilirubin. 3. Bilifuscin obtained from ester-form bilirubin displayed the absorpton maximum at 331 mu by the ester combination, but the proper absorption maximum with the rise of absorption curve tending to the side of short wave length from 280 mμ was not observed. The absorption curve of propentdyopent product did not show the proper absorption maximum, except the absorption maximum of ester combination, but it's absorption maximum displayed at 523 mμ after pentdyopent reaction. 4. Ester-form bilirubin resolved into biliverdin, a product with the complicated small absorption maximum between 612 and 592 mμ and a product with the absorption maximum at 400 mμ by the oxidation of oxygan, and it turned to bilifuscin through pentdyopent product on the further oxidation. 5. Bilirubin and biliverdin were identified by chromatography in alkaline solution of ester-form bilirubin after the disappearance of it's absorption maximum and the display of negative diazo reaction.
Published Date
1959-10-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume71
Issue
issue11-2
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
7673
End Page
7688
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/71/11-2/71_11-2_7673/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma