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ID 41110
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Title Alternative
Studies on Leukemia Part 3. Clinical and Chemical Study of Leukemia and Blood Diseases
Author
Wakimoto, Takeo
Abstract
The author studied changes in serum phosphatase and transaminase in the blood diease, especially leukemia, that had been diagnosed as suchmainly by bone-marrow tissue culture and a new hematological technique devised in the Hiraki Clinic of Internal Medicine, and obtained the following results. 1. In leukemia alkaline phosphatase is slightly decreased while acid phosphatase is slightly increased. However, only in monocytic leukemia these phosphatases are generally normal. In transaminase both glutamic oxalacetic transaminase and glutamic pyruvic transaminase are increased, but such increase is marked in acute myelogenous leukemia followed by monocytic leukemia and chromic myelogenous leukemia, while those in lymphocytic leukemia are normal. From these differences it can be assumed that there are differences in the enzyme system mainly acting upon different leucocyte series. 2. In hypoplastic anemia phosphatase is generally at the normal level, but transaminase is increased, suggesting tissue destruction similar to Banti's disease and hemolytic anemia. In contrast to this, transaminase in idopathic hypochromic anemia transaminase is hardly changed. 3. In cancer disease, only a slight decrease in both phosphatase and transaminase can be observed, but in hepatoma and in the cases with meatastasis into the liver, alkaline phosphatase and transaminase increase in parallel to obstructive jaundice. 4. In lymphogranulomatosis so long as jaundice is not accompanied, phosphatase and transaminase are within the normal range, and in idiopathic thrombocytopenic purpura a slight decrease in alkaline phosphatase can be recognized.
Published Date
1959-08-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume71
Issue
issue9-1
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
5545
End Page
5553
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/71/9-1/71_9-1_5545/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma