start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=10-1 article-no= start-page=6361 end-page=6365 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590920 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Serological Studies on the Liver Antibody Part 3. Studies on the Azo-dye Labelled Liver Antibody kn-title=肝臓抗体に関する血清学的研究 第3編 アゾ色素標識肝抗体について en-subtitle= kn-subtitle= en-abstract= kn-abstract=With the use of Atoxyl antibody obtained from the rabbit immunized with Atoxyl labeled egg-white albumin the author traced the changes of Atoxyl in the blood and oragns of the rabbit inoculated with Atoxyl labeled normal rabbit serum and homologus liver antiserum. As the results it has been clarified that the liver antiserum does not reveal absolute visceral specificity but it shows a relative visceralspecificity and also it tends to disturb the liver function. en-copyright= kn-copyright= en-aut-name=TaninoMitsuhiro en-aut-sei=Tanino en-aut-mei=Mitsuhiro kn-aut-name=谷野光弘 kn-aut-sei=谷野 kn-aut-mei=光弘 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=10-1 article-no= start-page=6353 end-page=6360 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590920 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Serological Studies on the Liver Antibody Part 2. Studies on the Homologous Liver Antibody kn-title=肝臓抗体に関する血清学的研究 第2編 同種肝抗体について en-subtitle= kn-subtitle= en-abstract= kn-abstract=With the purpose to elucidate the in vivo antigenicity of homologous animal organs, especially of the liver, and also to clarify the problem centering around the visceralspecificity and the harful effect of the homologous liver antiserum obtained from the same species of animals sensitized with the homologous animal antigens, the author carried out serological investigations, and obtained the following results. 1. Antigenicity can be recongized in the liver of the same species of animals, but its antibody titer is lower than that of different species of animals; and moreover, the in vivo reactions between such a liver antiserum and various visceral antigens of rabbits reveal a relative visceral specificity. 2. When the same species of animal is sensitized with antigen extracted from the rabbit liver, homologous liver antibody can be detected not only in the circulating blood but also in various organ tissues of the rabbit. 3. When the homologous liver antiserum obtained from the same species of animal sensitized with the antigen extracted from rabbit liver is inoculated into the same species of rabbits, disturbances in the liver and neighboring internal organs can be recognized serologically and functionally. Moreover, the serum of such animals possesses the relative visceral specificity. en-copyright= kn-copyright= en-aut-name=TaninoMitsuhiro en-aut-sei=Tanino en-aut-mei=Mitsuhiro kn-aut-name=谷野光弘 kn-aut-sei=谷野 kn-aut-mei=光弘 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=10-1 article-no= start-page=6343 end-page=6352 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590920 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Serological Studies on the Liver Antibody Part 1. A Study on the Heterogenous Liver Antibody kn-title=肝臓抗体に関する血清学的研究 第1編 異種肝抗体について en-subtitle= kn-subtitle= en-abstract= kn-abstract=In order to see whether or not the liver of different species of animals possesses antigenicity and also to study the significance of senstization with visceral antigens, the visceral specificity of liver antiserum, and the possible visceral disturbances the author carried out serological study on different species of animals (dogs and rabbits) and obtained the following results. 1. The liver of different species of animals possesses antigenicity, aud the serum of the rabbit sensitized with dog liver extract shows a relative visceral specificity in the reaction in vitro between this serum and the extracts of various organs, blood, and serum of the dog. 2. In the blood as well as in various organ tissues of the rabbit sensitized by the extract of dog liver can be detected antibody (liver antibody) as to react with such sentitizing agents. 3. When the serum of the rabbit sensitized with dog liver extract is inoculated into a normal dog, it disturbs the function of the liver and neighboring abdominal organs. Moreover, such a serum accelerates the production of antibody to react especially with the antigen extracted from the dog liver and also it reveals a relative visceral specificity. en-copyright= kn-copyright= en-aut-name=TaninoMitsuhiro en-aut-sei=Tanino en-aut-mei=Mitsuhiro kn-aut-name=谷野光弘 kn-aut-sei=谷野 kn-aut-mei=光弘 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 END