このエントリーをはてなブックマークに追加
ID 17568
Eprint ID
17568
FullText URL
Thumnail 85_211.pdf 603 KB
Title Alternative
Studies on Basophilic Leucocytes Part. Ⅲ. Changes of Basophilic Leucocytes in Chronic Myelogenous Leukemia
Author
Tanizaki, Yoshiro
Abstract
Basophils in peripheral blood and bone marrow in 25 cases with chronic myelogenous leukemia (CML) were counted and morphologically classified by our improved method; basophilis were classified into Ⅰ to Ⅴ types. The Ⅲ and Ⅳ types were subclassified to S type with sharply defined granules and diffuse N type. This classification was adapted for basophilograms. The basophilogram in healthy controls showed a left type and that in CML generally a right type. It shifted to the left approaching to the normal type in the cases with remission by chemotherapy. In relapsing patients with CML, the basophilogram clearly shifted to the right. The basophilogram seen in 2 cases with the pre-stage of blastic crisis of CML indicated a definite right type. It was shown that an increase of S type occurred in the relapsing stage. Therefore, appearance of S type as well as a right type in basophilogram would be a useful clue to follow CML patients clinically. A basophils of S type was considered to be immature. The bone marrow basophilogram was shown to be more shifted to the right than that of peripheral blood, and this tendency became more remarkable in relapse. Presence of a right type in basophilogram and appearance of S type are significant to observe the clinical course in CML patients, especially for judging acute exacerbation.
Published Date
1973-06-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume85
Issue
issue5-6
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
211
End Page
221
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/85/5-6/85_5-6_211/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma