このエントリーをはてなブックマークに追加
ID 18463
Eprint ID
18463
FullText URL
Thumnail 72_131.pdf 488 KB
Title Alternative
Studies on the Antiseptic Action and Toxicity of Mercuric Chloride Part 2. The Toxicity of Mercuric Chloride and Antidotal Effect of 6.8-dithiooctanoic Acid
Author
Sakai, Asao
Abstract
For the purpose of determining the toxicity of mercuric chloride the author performed experiments to find out LD(50) of this compound with the mice given intraperitoneal injection of mercuric chloride solution and also experiments on the antidotal effect of 6.8-dithiooetanoic acid: and obtained the following results. 1. The LD(50) values determined by Van den Waerdens method are as follows: 1 day LD(50)=0.01116±0.00102mg 2 day LD(50)=0.00997±0.001036mg 3 day LD(50)=0.00837±0.00108mg 4 day LD(50)=0.00712±0.00109mg 5 day LD(50)=0.0064±0.00109mg 6 day LD(50)=0.00574±0.00125mg 2. When 6.8-dithiooctanoic acid is injected to mice prior to intraperitoneal injection of the mercuric chloride solution, it has been found that fatality rate and toxic symptoms (adecrease in the erythrocyte count and an increase in the leucocyte count) are somewhat suppressed.
Published Date
1959-12-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume72
Issue
issue1
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
131
End Page
138
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/72/1/72_1_131/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma