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ID 40737
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Title Alternative
Daily changes of lung guanidino compounds in rats in acute renal failure
Author
Kosogabe, Yoshinori
Abstract
Renal failure causes various metabolic disorders, especially increases of uremic toxins. Of the uremic toxins, guanidino compounds have a main role in uremia. Although lung injury is often complicated by renal failure, the role of guanidino compounds in lung injury is obscure. I have studied the changes in guanidino compounds in the lung of rat with ischemic acute renal failure. Guanidino compounds increased the first day after ischemia, but methylguanidine, which is the most toxic guanidino compound, showed a delayed increase in the lung. These results suggest the de novo synthesis of methylguanidine in the lung. A guanidinogram may by useful to judge changes in guanidino compounds.
Keywords
急性腎不全
グアニジノ化合物
メチルグアニジン
Published Date
1989-04
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume101
Issue
issue3-4
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
379
End Page
385
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/101/3-4/101_3-4_379/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma