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ID 41184
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Title Alternative
Conversion of (14)C-Labelled Glucose to Amino Acid in Brain Tissue Part 1. Conversion of (14)C-labelled Glucose to Amino Acid by Homogenate of human and Rabbits Brain
Author
Kuroda, Takaaki
Abstract
The conversion of (14)C-labelled glucose to free amino acids by homogenate of human and rabbit brain was studied by paper chromatgraphy and radioautography with X-ray film. Results were: 1) In both human and rabbit brain glutamine, asparagine, glutamic acid, aspartic acid and γ-aminobutyric acid with radioactivity were derived from (14)C-labelled glucose. Moreover in rabbit brain alanine was also derived. 2) In normal rabbit brain the derived amino acids were investigated. During short incubate time the precoursors such as aspartic acid and glutamic acid appeared quickly and intensively. Next asparagine and glutamine showed up and then alanine and γ-aminobutyric acid were proved. 3) It needed 24 hours for all free amino acids to appear sharply. 4) The optimal pH of this reaction was 8.5-9.0
Published Date
1959-09-20
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume71
Issue
issue10-1
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
6449
End Page
6454
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/71/10-1/71_10-1_6449/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma