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ID 30852
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Author
Itoshima, Tatsuya
Fedail, Sulieman S.
Suliman, Ikhlas
Ali, Abbas K.
Higashi, Toshihiro
Tsuji, Takao
Abstract

Markers of hepatitis A and B virus were tested in 88 adult Sudanese subjects in Khartoum, Sudan. The subjects consisted of 25 control hospitalized patients, 21 volunteer blood donors, 23 patients with hepatosplenic schistosomiasis, 13 patients with liver cirrhosis and 6 patients with hepatocellular carcinoma (HCC). Antibody to hepatitis A virus was detected in 96% of the total. Hepatitis B surface antigen (HBsAg) was positive in 4, 24, 22, 31, and 67% of the subject groups, respectively. Antibody against hepatitis B core antigen (HBcAb) of undiluted serum was positive in 60, 57, 65, 77 and 83%, and there was no difference in incidence among the groups. It was positive in 200X diluted serum in 4, 24, 17, 23 and 60%. HBsAg and HBcAb (200X) were detected more often in HCC patients than in the control subjects (p less than 0.01). Hepatitis B virus is an important factor in the etiology of HCC in the Sudan.

Keywords
hepatitis B virus markers
liver cirrhosis
hepatocellular carcinoma
schistosomiasis
Sudan
Amo Type
Article
Published Date
1989-08
Publication Title
Acta Medica Okayama
Volume
volume43
Issue
issue4
Publisher
Okayama University Medical School
Start Page
241
End Page
244
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
英語
File Version
publisher
Refereed
True
PubMed ID
Web of Sience KeyUT