JaLCDOI 10.18926/AMO/56078
FullText URL 72_3_309.pdf
Author Katayama, Satoshi| Takenaka, Tadasu| Nakamura, Aya| Sako, Sinichi| Bessho, Akihiro| Ohara, Nobuya|
Abstract Pulmonary tumor thrombotic microangiopathy (PTTM) is a fatal, malignancy-related respiratory complication; we herein report a PTTM case induced by metastatic prostate cancer. An 81-year-old Japanese man developed dyspnea. High-resolution computed tomography (HRCT) revealed ground-glass opacities spread across bilateral lung fields. Pulmonary microvascular aspiration cytology detected prostate cancer cells. As PTTM was highly suspected, docetaxel chemotherapy was performed immediately. His respiratory condition and HRCT findings improved temporarily, but he died approx. 6 weeks after admission. Autopsy showed fibrocellular intimal proliferation of small pulmonary arterioles, which confirmed the diagnosis of PTTM induced by prostate cancer. As in the present case, it is often difficult to confirm the presence of not only tumor embolization but also fibrocellular intimal proliferation before the patient’s death.
Keywords autopsy dyspnea prostate neoplasm metastatic lung cancer thrombotic microangiopathy
Amo Type Case Report
Published Date 2018-06
Publication Title Acta Medica Okayama
Volume volume72
Issue issue3
Publisher Okayama University Medical School
Start Page 309
End Page 313
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2018 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 29926010
JaLCDOI 10.18926/AMO/31843
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Tanaka, Shouichi| Bessho, Akihiro| Takahashi, Hideaki| Ohta, Takeyuki| Takada, Rie| Murakami, Ichiro|
Abstract <p>We report 2 cases of small cell carcinoma (SmCC) of the stomach with distant metastasis that were treated with the same chemotherapeutic regimens as used to treat small cell lung cancer. Although the mean survival of patients with SmCC of the stomach is reported to be only 7 months, our patients survived for 15 and 14 months, respectively. In our experience, these chemotherapeutic regimens might provide a survival benefit for patients with SmCC of the stomach, although they demonstrated no remarkable antitumor effects.</p>
Keywords small cell carcinoma extrapulmonary small cell carcinoma neuroendocrine cell carcinoma gastric cancer
Amo Type Case Report
Published Date 2009-10
Publication Title Acta Medica Okayama
Volume volume63
Issue issue5
Publisher Okayama University Medical School
Start Page 293
End Page 298
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 19893606
Web of Sience KeyUT 000271132000010