Okayama University Medical School Acta Medica Okayama 0386-300X 72 1 2018 The Usefulness of Readout-Segmented Echo-Planar Imaging (RESOLVE) for Bio-phantom Imaging Using 3-Tesla Clinical MRI 53 59 EN Yuuki Yoshimura Radiological Technology, Graduate School of Health Sciences, Okayama University Masahiro Kuroda Radiological Technology, Graduate School of Health Sciences, Okayama University Irfan Sugiantoc Department of Oral and Maxillofacial Radiology, Okayama University Babatunde O. Bamgbosec Department of Oral and Maxillofacial Radiology, Okayama University Kanae Miyahara Radiological Technology, Graduate School of Health Sciences, Okayama University Yuichi Ohmura Radiological Technology, Graduate School of Health Sciences, Okayama University Akira Kurozumi Radiological Technology, Graduate School of Health Sciences, Okayama University Toshi Matsushita Central Division of Radiology, Okayama University Hospital Seiichiro Ohno Central Division of Radiology, Okayama University Hospital Susumu Kanazawa Department of Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Junichi Asaumi Department of Oral and Maxillofacial Radiology, Okayama University Original Article 10.18926/AMO/55663 Readout-segmented echo-planar imaging (RESOLVE) is a multi-shot echo-planar imaging (EPI) modality with k-space segmented in the readout direction. We investigated whether RESOLVE decreases the distortion and artifact in the phase direction and increases the signal-to-noise ratio (SNR) in phantoms image taken with 3-tesla (3T) MRI versus conventional EPI. We used a physiological saline phantom and subtraction mapping and observed that RESOLVE’s SNR was higher than EPI’s. Using RESOLVE, the combination of a special-purpose coil and a large-loop coil had a higher SNR compared to using only a head/neck coil. RESOLVE’s image distortioas less than EPI’s. We used a 120 mM polyethylene glycol phantom to examine the phase direction artifact.vThe range where the artifact appeared in the apparent diffusion coefficient (ADC) image was shorter with RESOLVE compared to EPI. We used RESOLVE to take images of a Jurkat cell bio-phantom: the cell-region ADC was 856×10−6mm2/sec and the surrounding physiological saline-region ADC was 2,951×10−6mm2/sec. The combination of RESOLVE and the 3T clinical MRI device reduced image distortion and improved SNR and the identification of accurate ADC values due to the phase direction artifact reduction. This combination is useful for obtaining accurate ADC values of bio-phantoms. No potential conflict of interest relevant to this article was reported.