JaLCDOI 10.18926/AMO/58275
FullText URL 74_2_159.pdf
Author Thar Htet San| Ota, Yoko| Fushimi, Soichiro| Fujisawa, Masayoshi| Yanai, Hiroyuki| Toda, Hiroko| Kunitomo, Tadayoshi| Kodama, Keisuke| Matsukawa, Akihiro|
Abstract Juvenile granulosa cell tumors (JGCTs) are rare ovarian tumors with overall good prognoses. They differ from adult granulosa cell tumors (AGCTs), which are well known for late recurrence. Most JGCTs (~97%) occur in individuals <30 years old. We report a recurrent JGCT in a 40-year-old woman 5 years after initial presentation. The histological appearance and lack of 402C>G missense point mutation of FOXL2 gene (characteristic of AGCT but absent in JGCT) allowed differentiation from AGCT. This is the first comprehensive report of JGCT with late recurrence. Although rare, late recurrence of JGCT can occur; long-term surveillance is suggested.
Keywords juvenile granulosa cell tumor late recurrence adult granulosa cell tumor
Amo Type Case Report
Published Date 2020-04
Publication Title Acta Medica Okayama
Volume volume74
Issue issue2
Publisher Okayama University Medical School
Start Page 159
End Page 163
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2020 by Okayama University Medical School
File Version publisher
Refereed True
FullText URL fulltext.pdf
Author Yoshimura, Teizo| Nakamura, Kaoru| Li, Chunning| Fujisawa, Masayoshi| Shiina, Tsuyoshi| Imamura, Mayu| Li, Tiantian| Mukaida, Naofumi| Matsukawa, Akihiro|
Keywords macrophages chemokines cytokines inflammation tumor microenvironment breast cancer
Published Date 2019-12-16
Publication Title International Journal of Molecular Sciences
Volume volume20
Issue issue24
Publisher MDPI
ISSN 1422-0067
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2019 by the authors.
File Version publisher
PubMed ID 31888216
DOI 10.3390/ijms20246342
Web of Science KeyUT 000506840100235
Related Url isVersionOf https://doi.org/10.3390/ijms20246342