JaLCDOI 10.18926/AMO/31980
FullText URL fulltext.pdf
Author Shinomiya, Kazuaki| Fujimura, Katsuyuki| Kim, Yonsu| Kamei, Chiaki|
Abstract <p>The present study was performed to investigate the effects of valerian extract on the sleep-wake cycle using sleep-disturbed model rats. A significant shortening in sleep latency was observed with valerian extract at doses of 1000 and 3000 mg/kg. On the other hand, valerian extract had no significant effects on total times of wakefulness, non-rapid eye movement (non-REM) sleep, or REM sleep, even at a dose of 3000 mg/kg. Valerian extract at doses of 1000 and 3000 mg/kg showed a significant increase in the delta activity during non-REM sleep. In conclusion, valerian extract may be useful as an herbal medicine having not only sleep-inducing effects but also sleep quality-enhancement effects.</p>
Keywords delta activity insomnia sleep latency sleep quality sleep-disturbed model valerian
Amo Type Article
Published Date 2005-06
Publication Title Acta Medica Okayama
Volume volume59
Issue issue3
Publisher Okayama University Medical School
Start Page 89
End Page 92
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 16049561
Web of Science KeyUT 000230039100003