JaLCDOI 10.18926/AMO/57367
FullText URL 73_5_383.pdf
Author Fu, Li| Nishibori, Masahiro|
Abstract High mobility group box-1 (HMGB1) is a non-histone, DNA-binding nuclear protein belonging to the family of damage-associated molecular patterns (DAMPs). HMGB1 has been reported to play an important role during epileptogenesis although the mechanisms of its actions are still not clear. Many hypotheses have been suggested especially about the relationship between HMGB1 and inflammation responses and blood-brain barrier disruption during epileptogenesis. In this review, we will mainly discuss the role of HMGB1 in epileptogenesis.
Keywords HMGB1 epileptogenesis inflammation blood-brain barrier
Amo Type Review
Published Date 2019-10
Publication Title Acta Medica Okayama
Volume volume73
Issue issue5
Publisher Okayama University Medical School
Start Page 383
End Page 386
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 31649363
Web of Sience KeyUT 000491886600002
Author Chen, Ling| Kasai, Tomonari| Li, Yueguang| Sugii, Yuh| Jin, Guoliang| Okada, Masashi| Vaidyanath, Arun| Mizutani, Akifumi| Satoh, Ayano| Kudoh, Takayuki| Hendrix, Mary J. C.| Salomon, David S| Fu, Li| Seno, Masaharu|
Published Date 2012-04-12
Publication Title PLoS ONE
Volume volume7
Issue issue4
Content Type Journal Article