JaLCDOI 10.18926/AMO/31596
FullText URL fulltext.pdf
Author Miyamoto, Osamu| Itano, Toshifumi| Fujisawa, Mutsuo| Tokuda, Masaaki| Matsui, Hideki| Nagao, Seigo| Hatase, Osamu|
Abstract <p>Basic fibroblast growth factor (bFGF) and nerve growth factor (NGF) were administered into the rat brain following unilateral fimbria-fornix transection. Both bFGF and NGF stimulated the sprouting of acetylcholinesterase (AChE) positive fibers in the hippocampus on the lesioned side. Furthermore, a small number of AChE-positive fibers were regenerated even when only the vehicle was administered. Rats treated with NGF as well as control group had only thin fibers, whereas those treated with bFGF had not only thin fibers but also thick fibers. These results indicate that intrinsic NGF is released and acts on damaged neurons directly, while bFGF acts them on directly and/or indirectly after brain injury.</p>
Keywords bFGF NGF regeneration acetylcholinesterase positive fibers sprouting
Amo Type Article
Published Date 1993-06
Publication Title Acta Medica Okayama
Volume volume47
Issue issue3
Publisher Okayama University Medical School
Start Page 139
End Page 144
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 8379341
Web of Science KeyUT A1993LL12400001
JaLCDOI 10.18926/AMO/30775
FullText URL fulltext.pdf
Author Ohkawa, Motoomi| Fujiwara, Naomi| Katoh, Tsutomu| Mori, Yasutane| Nakano, Satoru| Tanabe, Masatada| Honjo, Yasumasa| Nagao, Seigo|
Abstract <p>High-resolution magnetic resonance venography (HR-MRV) of intracranial subependymal veins using a two-dimensional Fourier-transform time-of-flight technique was performed on normal volunteers and clinical cases of cerebral disease. For the pulse sequence, fast-field-echo sequence was used with the following parameters: TR/TE/ flip angle = 34ms/12ms/50deg., 256 x 256 matrix, 1 mm effective slice thickness, 150mm field of view, and one signal acquisition. Sequential vertical coronal sections were taken against the skull base. The anterior septal vein, the medial atrial vein, the anterior caudate vein and thalamostriate vein were detected in all subjects. In all clinical cases, HR-MRV was equal in diagnostic capability to conventional cerebral angiography.</p>
Keywords high-resolution MR venography MR angiography subependymal veins
Amo Type Article
Published Date 1997-12
Publication Title Acta Medica Okayama
Volume volume51
Issue issue6
Publisher Okayama University Medical School
Start Page 321
End Page 325
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 9439774
Web of Science KeyUT 000071183400005