JaLCDOI 10.18926/AMO/31139
FullText URL fulltext.pdf
Author Odaka, Koji| Hiramatsu, Yuji| Eguchi, Katsuto| Kudo, Takafumi|
Abstract <p>The effects of epidermal growth factor (EGF) on neonatal intestines were examined in the rat. In 5-day-old rats, sucrase, trehalase, alkaline phosphatase (ALP) and gamma-glutamyl transpeptidase (gamma-GTP) activities in the small intestines were significantly increased after subcutaneous injection of EGF for 3 days (1 microgram/rat/day). gamma-GTP activity was also accelerated after oral EGF administration (2 micrograms/rat/day). Small intestines of 12-day-old rats injected with EGF for 10 days (1 microgram/rat/day) were significantly heavier than those of controls. These results suggest that EGF influences neonatal growth improving enlargement and functional development of their intestines.</p>
Keywords epidermal growth factor neonate intestine breast milk rat
Amo Type Article
Published Date 1994-02
Publication Title Acta Medica Okayama
Volume volume48
Issue issue1
Publisher Okayama University Medical School
Start Page 47
End Page 50
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 7910714
Web of Sience KeyUT A1994MY85100008