JaLCDOI 10.18926/AMO/30294
FullText URL fulltext.pdf
Author Hiraki, K.| Ofuji, T.| Kobayashi, T.| Sunami, H.| Awai, K.|
Abstract <p>The idiopathic thrombocytopenic purpura was described by Werlhof as an independent disease first in 1738. Kaznelson reported the excellent effect of splenectomy for its chronic type in 1915. For the genesis of its thrombocytopenia, there have been many theories to be concluded into the followings, 1) the development of an auto-immune mechanism resulting in platelet destruction, 2) increased platelet destruction in the spleen, 3) the inhibition of platelet production from the marrow megakaryocytes by a humoral factor produced in the spleen, 4) both increased destruction and decreased production of the platelet. Among the above four theories, the third one is the most popular in the chronic type.</p>
Amo Type Article
Published Date 1956-04
Publication Title Acta Medicinae Okayama
Volume volume10
Issue issue2
Publisher Okayama University Medical School
Start Page 57
End Page 61
NCID AA00041342
Content Type Journal Article
language 英語
File Version publisher
Refereed True
NAID 120002305337