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ID 31428
FullText URL
Author
Tsuji, Takao
Tokuyama, Katsuyuki
Okada, Takeshi
Takata, Shinji
Naito, Kunihiko
Kosaka, Kiyowo
Takahashi, Takashi
Mayumi, Makoto
Abstract

Hepatitis B core antigen (HBc Ag) and hepatitis B surface antigen (HBs Ag) were detected in the liver tissue of a patient with chronic aggressive hepatitis by the immunofluorescent complement technique. The presence of anti-HBc was examined by the same method in 67 human sera previously tested for HBs Ag, anti-HBs and s-GPT levels. HBc Ag was localized mainly in the nucleus and sometimes in the cytoplasm of the hepatic cells. HBs Ag was found only in the cytoplasm. The focal area of HBc Ag positive hepatic cells seemed to correspond to the HBs Ag positive cells. Double staining demonstrated the simultaneous presence of HBs Ag and HBc Ag in individual cells. Anti-HBc positive serum was found in 46 (68.7%) cases. Forty-eight (71.6%) indicated a combination of HBs Ag and anti-HBc.

Published Date
1976-02
Publication Title
Acta Medica Okayama
Volume
volume30
Issue
issue1
Publisher
Okayama University Medical School
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
英語
File Version
publisher
Refereed
True
PubMed ID
Amo Type
Original Article
Submission Path
amo/vol30/iss1/6