JaLCDOI 10.18926/AMO/31137
FullText URL fulltext.pdf
Author Perdomo, Jose A| Hizuta, Akio| Iwagaki, Hiromi| Takasu, Shinji| Nonaka, Yasuyuki| Kimura, Toshikazu| Takada, Shigemi| Moreira, Luis F| Tanaka, Noriaki| Orita, Kunzo|
Abstract <p>The records of 159 patients who underwent surgical resection of colorectal cancer were reviewed to assess the incidence of ovarian metastasis and to define the role of oophorectomy. Four of these patients presented with metachronous metastases, and one patient had synchronous ovarian involvement. The incidence of ovarian involvement was higher in younger patients. While most patients with ovarian involvement had the primary tumor located at the rectosigmoid region, a similar distribution of the primary tumor was observed in patients without ovarian metastasis. The histological type and degree of differentiation was similar regardless of whether or not ovarian metastasis was present. Of the patient without ovarian metastasis, 57% presented with nodal metastases and 3.2% with peritoneal dissemination, while all patients with ovarian metastasis had nodal and peritoneal involvement. Our results suggest that histological type and degree of differentiation of the primary tumor do not influence likelihood of ovarian metastasis. However, the exposure of the tumor to the serosal surface and the subsequent peritoneal dissemination may be an important route by which malignant tumor cells reach the ovaries. However, due to the wide lymphatic involvement in patients with ovarian metastasis, the lymphatic route may be important as well. Thus, we consider that oophorectomy should be performed in all postmenopausal women, when the ovaries are macroscopically affected, and in premenopausal patients with Astler-Coller B2 tumors or over.</p>
Keywords colorectal carcinoma metastasis ovarian cancer surgical treatment
Amo Type Article
Published Date 1994-02
Publication Title Acta Medica Okayama
Volume volume48
Issue issue1
Publisher Okayama University Medical School
Start Page 43
End Page 46
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 8191916
Web of Sience KeyUT A1994MY85100007