JaLCDOI 10.18926/AMO/31124
FullText URL fulltext.pdf
Author Ariki, Norifumi| Iwagaki, Hiromi| Yoshino, Tadashi| Nonaka, Yasuyuki| Fujiki, Shigeatsu| Perdomo, Jose Antonio| Hizuta, Akio| Tomoda, Jun| Tanaka, Noriaki| Tsuji, Takao| Orita, Kunzo|
Abstract <p>Endoscopical segmental piecemeal tumorectomy (ESPT) for nodular elevation of colorectal tumor is advantageous in terms of minimizing both surgical invasion and postoperative burden to the patients. Nodular elevation of colorectal tumors is said to occur when the body of the tumor is adenomatous and the surface of the focal cancer grows more horizontally into the lumen than vertically. We report here four cases of nodular elevation of colorectal tumors which were each treated by different surgical procedures.</p>
Keywords nodular elevation coloretal tumors endoscopical segmental piecemeal tumorectomy
Amo Type Article
Published Date 1994-06
Publication Title Acta Medica Okayama
Volume volume48
Issue issue3
Publisher Okayama University Medical School
Start Page 169
End Page 171
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 7942075
Web of Sience KeyUT A1994NV04300009
JaLCDOI 10.18926/AMO/31094
FullText URL fulltext.pdf
Author Iwagaki, Hiromi| Hizuta, Akio| Iwadou, Hironori| Perdomo, Jose Antonio| Tanaka, Noriaki| Orita, Kunzo|
Abstract <p>In this study, we investigated serum-soluble interleukin-2 receptor (sIL-2r) and neopterin (NPT) levels in five patients with severe postoperative infections. A total of 25 synchronous determinations of sIL-2r and NPT were performed. A marked increase in sIL-2r and NPT levels was observed, and the increase in sIL-2r was significantly correlated to that of NPT which is a marker of macrophage activity. These results suggest that macrophages are involved in the stimulation of sIL-2r release, representing a potentially negative biological effect. The results indicate that sIL-2r may be a useful indicator of the efficacy of antibiotics and of prognosis.</p>
Keywords soluble interleukin-2 receptor neopterin intection
Amo Type Article
Published Date 1994-08
Publication Title Acta Medica Okayama
Volume volume48
Issue issue4
Publisher Okayama University Medical School
Start Page 225
End Page 226
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 7817778
Web of Science KeyUT A1994PE51400008
JaLCDOI 10.18926/AMO/31090
FullText URL fulltext.pdf
Author Perdomo, Jose Antonio| Iwagaki, Hiromi| Hizuta, Akio| Tanaka, Noriaki| Orita, Kunzo|
Abstract <p>Familial adenomatous polyposis (FAP) is a well-known autosomal dominant disorder characterized by the formation of multiple adenomatous polyps of the colon. Gardner's syndrome is a variant of familial polyposis coli, and both can be associated with colonic or extracolonic benign and/or malignant tumors. It has been widely recognized that an adenocarcinoma of the colon develops in virtually all cases, usually at an earlier age, if polyps are left untreated. Families of four individuals diagnosed of FAP were surveyed and 56 relatives of the families were examined. Of these 56, 21 had multiple colon polyps, 3 of whom had early-stage adenocarcinomas. We consider that familial survey of FAP individuals can be of considerable benefit for this high-risk population due to the autosomal nature of the disease, allowing diagnosis of an associated cancer at an earlier stage.</p>
Keywords familial adenomatous polyposis colorectal carcinoma Gardner's syndrome
Amo Type Article
Published Date 1994-08
Publication Title Acta Medica Okayama
Volume volume48
Issue issue4
Publisher Okayama University Medical School
Start Page 227
End Page 229
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 7817779
Web of Science KeyUT A1994PE51400009
JaLCDOI 10.18926/AMO/30494
FullText URL fulltext.pdf
Author Iwagaki, Hiromi| Hizuta, Akio| Fujiwara, Toshiyushi| Perdomo, Jose Antonio| Tanaka, Noriaki| Orita, Kunzo|
Abstract <p>Patients with far advanced colorectal cancers received chemotherapy consisting of low-dose cyclophosphamide (LDCY) 333 mg/m2 every four weeks intravenously and by oral administration of 5'-DFUR (a masked compound of 5-Fluorouracil). Serum levels of immunosuppressive acidic protein (IAP), an acute phase protein, were measured every four weeks for a total of thirty-one LDCY trials of ten patients. LDCY chemotherapy significantly decreased the IAP levels in cancer patients with high IAP levels. These results suggested that LDCY chemotherapy could counteract host responses against tumors and could have decreased immunosuppressive responses in cancer patients.&#60;/P&#62;</p>
Keywords low-dose cyclophosphamide< acute phase protein immunosuppressive acidic protein
Amo Type Article
Published Date 1996-10
Publication Title Acta Medica Okayama
Volume volume50
Issue issue5
Publisher Okayama University Medical School
Start Page 271
End Page 272
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 8914681
Web of Science KeyUT A1996VQ20600007
JaLCDOI 10.18926/AMO/30394
FullText URL fulltext.pdf
Author Perdomo, Jose Antonio| Iwagaki, Hiromi| Hizuta, Akio| Mizuno, Motowo| Nakagawa, Hitoshi| Tanaka, Noriaki| Tsuji, Takao| Orita, Kunzo|
Abstract <p>The medical records of 16 consecutive patients with Crohn's disease surgically treated in our department from 1978 to 1993 were retrospectively reviewed. The indication for surgery was obstructive symptoms due to Crohn's strictures that were unresponsive to conservative therapy. The types of operations performed were classified into five categories. Nine patients (56.3%) had small bowel resection only, 4 (25.0%) underwent an ileocolonic resection, 1 (6.3%) had a total colectomy, 1 (6.3%) had Mile's operation and 1 (6.3%) had subtotal gastrectomy with gastrojejunostomy and antral mucosectomy. Of these 16 patients, 13 (81.3%) had resection with a single anastomosis and strictureplasty was concomitantly performed in only 2 cases (12.5%). Crohn's disease recurred in 3 patients (18.8%), 1 of whom required a second operation.</p>
Keywords Crohn's disease surgical resection strictureplasty recurrence
Amo Type Article
Published Date 1995-04
Publication Title Acta Medica Okayama
Volume volume49
Issue issue2
Publisher Okayama University Medical School
Start Page 113
End Page 115
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 7618489
Web of Science KeyUT A1995QV69800008