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ID 30542
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Author
Miyamoto, Kanji
Miyano, keiko
Tabuchi, Kazuo
Nishimoto, Akira
Yoshida, Haruhiko
Yumoto, Tokichi
Tanaka, Toshio
Abstract
Chromosome studies of a malignant lymphoma cell line derived from the brain were made by Q- and G-banding techniques. The modal number of chromosomes was 45. Complex structural rearrangements were present, but the 14q+ marker chromosome frequently seen in malignant lymphomas was not identified in the cell line. The main karyotype in cells analyzed was 45, X, -Y, del (2) (q21q23), t (3;?) (p25;?), t (p12;?), -8, 11q+, 18q+, +mar. Absence of the 14q+ may be explained by: firstly, clones which possessed 14q+ marker chromosome in brain tumor cells may have been selected out with increasing culture time and repeated passages; or secondly, the presence of the 14q+ marker chromosome depends on the type of lymphoma.
Keywords
brain lymphoma
tissue culture cell line
chromosome
negative 14q+.
Amo Type
Brief Note
Published Date
1980-04
Publication Title
Acta Medica Okayama
Volume
volume34
Issue
issue2
Publisher
Okayama University Medical School
Start Page
117
End Page
122
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
英語
File Version
publisher
Refereed
True
PubMed ID
Web of Sience KeyUT