| JaLCDOI | 10.18926/AMO/30670 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Harada, Yasuhiro| Tabuchi, Kazuo| Moriya, Yoshio| Furuta, Tomohisa| Kishikawa, Hidemi| Nishimoto, Akira| |
| Abstract | <p>The amount of S-100 protein in rat brain embolized with carbon microspheres decreased in parallel with the development of cerebral edema as judged by water content, recovering to the normal range by 24h after embolization. These results suggest the participation of S-100 protein in the permeability characterisitics of nervous system capillaries known as the blood-brain barrier.</p> |
| Keywords | S-100 protein blood-brain barrier cerebral edema |
| Amo Type | Article |
| Published Date | 1982-12 |
| Publication Title | Acta Medica Okayama |
| Volume | volume36 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 447 |
| End Page | 451 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 7158426 |
| Web of Sience KeyUT | A1982PW07500003 |
| JaLCDOI | 10.18926/AMO/30542 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Miyamoto, Kanji| Miyano, keiko| Tabuchi, Kazuo| Nishimoto, Akira| Yoshida, Haruhiko| Yumoto, Tokichi| Tanaka, Toshio| |
| Abstract | Chromosome studies of a malignant lymphoma cell line derived from the brain were made by Q- and G-banding techniques. The modal number of chromosomes was 45. Complex structural rearrangements were present, but the 14q+ marker chromosome frequently seen in malignant lymphomas was not identified in the cell line. The main karyotype in cells analyzed was 45, X, -Y, del (2) (q21q23), t (3;?) (p25;?), t (p12;?), -8, 11q+, 18q+, +mar. Absence of the 14q+ may be explained by: firstly, clones which possessed 14q+ marker chromosome in brain tumor cells may have been selected out with increasing culture time and repeated passages; or secondly, the presence of the 14q+ marker chromosome depends on the type of lymphoma. |
| Keywords | brain lymphoma tissue culture cell line chromosome negative 14q+. |
| Amo Type | Brief Note |
| Published Date | 1980-04 |
| Publication Title | Acta Medica Okayama |
| Volume | volume34 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 117 |
| End Page | 122 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 6450513 |
| Web of Sience KeyUT | A1980JY15600005 |
| JaLCDOI | 10.18926/AMO/32045 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Tsuboi, Masahiro| Moriya, Yoshio| Tabuchi, Kazuo| Nishimoto, Akira| |
| Abstract | <p>In order to locate the target cells for malignant transformation by BK virus (a human papova virus) in hamster brain, electron microscopic observation of tumor originally induced in hamster brain by BK virus was performed. With light microscopy, the BK virus-induced tumor (Vn 17) bore a close resemblance to human malignant ependymoma. Under the electron microscope, numerous microvilli and few cilia were visible on the surface of the tumor cells. These tumor cells were joined to each other by desmosomes. Gap junctions were not observed. Multilayered cuboidal cells were observed around the lumen and blood vessels in the tumor. With regard to fine structure, three types of Vn 17 cells were recognized; ependymal like cells, tanycytes with prominent cell processes, and undifferentiated cells with few cytoplasmic organelles. There was no basal lamina between the ependymal cells and the connective tissue stroma. The Vn 17 cells showed some similarity to the ultrastructural features of the epemdymal cells of newborn rabbits, suggesting that the target cells for Vn 17 may be cells related to ependyma. Malignant transformation of the cells would be initiated in the early stages after BK virus inoculation into the brain of newborn hamsters.</p> |
| Keywords | elevtron microscopy experimental brain tumor BK virus |
| Amo Type | Article |
| Published Date | 1979-12 |
| Publication Title | Acta Medica Okayama |
| Volume | volume33 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 423 |
| End Page | 430 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 231894 |
| NAID | 120002312316 |
| Author | Tabuchi, Kazuo| |
|---|---|
| Published Date | 1971-12 |
| Publication Title | Acta Medicinae Okayama |
| Volume | volume25 |
| Issue | issue6 |
| Content Type | Journal Article |
