JaLCDOI 10.18926/AMO/30998
FullText URL fulltext.pdf
Author Yamada, Teruo| Hirai, Yasuo| Sakano, Shigehiro| Kosaka, Makoto| Tada, Keiichi| Furutani, Sei| Kosaka, Futami|
Abstract <p>The direct determination by gas chromatography of blood levels of anesthetic agents has been difficult because of the water content of blood. In the present study, the method of Yokota et al. (1967) was modified by improving the packing materials of the column, the blood sample vaporizer and the flow-path during analysis. As a result, accurate and reproducible determination of halothane, enflurane and isoflurane dissolved in blood was achieved. With this system, blood in which halothane, enflurane and isoflurane had been dissolved could be analyzed without changing the column between samples. Moreover, each sample was prepared in less than 10 min, and more than 100 consecutive determinations could be made with excellent reproducibility. The coefficient of variation was less than 3.8%.</p>
Keywords determination halothane enflurance isoflurance gas chromatography
Amo Type Article
Published Date 1988-08
Publication Title Acta Medica Okayama
Volume volume42
Issue issue4
Publisher Okayama University Medical School
Start Page 183
End Page 192
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 3177003
Web of Science KeyUT A1988P884600001