JaLCDOI 10.18926/AMO/31932
FullText URL fulltext.pdf
Author Takahishi, Isao| Yorimitsu, Seiichi| Hara, Masamichi| Inagaki, Toshihiro| Nakada, Hiroyuki| Sekito, Noriko| Hayashi, Naoki| Nonaka, kenichi| Ohmoto, Eijiro| Uchida, Kouzaburo| Takizawa, Michihiro| Kimura, Ikuro| Sanada, Hiroshi| Adachi, Tomiro| Tsubota, Teruhiko| Kitajima, Koichi|
Abstract <p>Thirteen previously untreated patients aged 70 and above with acute nonlymphocytic leukemia were treated with aclarubicin (ACR) alone. Among 10 cases (3, acute myelocytic leukemia; 4, acute myelomonocytic leukemia; 2, acute monocytic leukemia; and one, acute erythroleukemia) in which an evaluation was possible, 5 cases (3, acute myelomonocytic leukemia; and 2, acute monocytic leukemia) obtained complete remission (CR). The CR rate was 83% in 6 patients with acute myelomonocytic leukemia or acute monocytic leukemia. The median CR duration and survival was 7.5 and 10 + months, respectively. Although side effects of the drug on digestive system such as nausea, vomiting and anorexia were observed in all patients, they were controllable by conventional treatments. The results suggest that ACR is effective for the clinical management of elderly patients with acute nonlymphocytic leukemia, especially those with acute myelomonocytic leukemia or acute monocytic leukemia.</p>
Keywords acute leukemia in elderly patients chemotherapy of acute leukemia aclarubicin
Amo Type Article
Published Date 1986-06
Publication Title Acta Medica Okayama
Volume volume40
Issue issue3
Publisher Okayama University Medical School
Start Page 175
End Page 177
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 3461685
Web of Science KeyUT A1986C914800006