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ID 19477
Eprint ID
19477
FullText URL
Thumnail 68_341.pdf 587 KB
Title Alternative
Experimental studies on Japanese B Encephalitis with radioactive P(32). 2. Nucleic acid metabolism, investigated by Schmidt & Thanhauser's method, in lung, spleen and kidney of the mouse infected with Japanese B Encephalitis
Author
Uchida, Yutaka
Abstract
Somewhat detailed knowledge was obtained on the nucleic acid metabolism in long, spleen and kidney of the infected mouse P(32) was used as the tracer and was injected to each mouse intraperitoneally various hours after the intracerebral inoculation of the virus. 6 and 24 hours after the injection of P(32) the organs were collected and fractionated by Schmidt-Thanhauser's method into RNA-phosphoprotein fraction and DNA fraction, which were then examined on their radioactivities. Just at the incubation stage or the visceral phase of Japanese B encephalitis the organs, lung, spleen and kidney, of the mouse proved to have high radioactivities, both in their RNA-phosphoprotein fractions and DNA fractions. It is interesting to note that the radioactivity in DNA fraction was observed to increase rather late in the incubation stage while the other appeared from the first of that stage on. The fact that in case of spleen higher radiotivity of RNA-phosphoprotein fraction than that of DNA fraction was observed should further be pointed out. In contrast to this, the high radioactivities in acidsoluble fractions also observed at the mcnbation stage remained unaltered even at the acme stage of the disease.
Published Date
1956-05-31
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume68
Issue
issue5
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
341
End Page
348
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/68/5/68_5_341/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma